ENSG00000241685


Homo sapiens

Features
Gene ID: ENSG00000241685
  
Biological name :ARPC1A
  
Synonyms : actin related protein 2/3 complex subunit 1A / ARPC1A / Q92747
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q22.1
Gene start: 99325910
Gene end: 99366262
  
Corresponding Affymetrix probe sets: 200950_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000408711
Ensembl peptide - ENSP00000262942
NCBI entrez gene - 10552     See in Manteia.
OMIM - 604220
RefSeq - NM_001190996
RefSeq - NM_006409
RefSeq Peptide - NP_001177925
RefSeq Peptide - NP_006400
swissprot - V9HVZ6
swissprot - Q92747
swissprot - E9PF58
Ensembl - ENSG00000241685
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arpc1aENSDARG00000008383Danio rerio
 ARPC1AENSGALG00000004693Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC004922.1ENSG0000028429272
ARPC1B / O15143 / actin related protein 2/3 complex subunit 1BENSG0000013042968


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017383  Actin-related protein 2/3 complex subunit 1
 IPR017986  WD40-repeat-containing domain
 IPR030140  Actin-related protein 2/3 complex subunit 1A
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030036 actin cytoskeleton organization TAS
 biological_processGO:0030833 regulation of actin filament polymerization IEA
 biological_processGO:0034314 Arp2/3 complex-mediated actin nucleation IEA
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 biological_processGO:0061024 membrane organization TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005885 Arp2/3 protein complex IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003779 actin binding TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0051015 actin filament binding IBA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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