ENSG00000130429


Homo sapiens

Features
Gene ID: ENSG00000130429
  
Biological name :ARPC1B
  
Synonyms : actin related protein 2/3 complex subunit 1B / ARPC1B / O15143
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q22.1
Gene start: 99374249
Gene end: 99394814
  
Corresponding Affymetrix probe sets: 201954_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000398110
Ensembl peptide - ENSP00000496599
Ensembl peptide - ENSP00000494033
Ensembl peptide - ENSP00000413173
Ensembl peptide - ENSP00000413067
Ensembl peptide - ENSP00000410238
Ensembl peptide - ENSP00000408758
Ensembl peptide - ENSP00000408508
Ensembl peptide - ENSP00000403324
Ensembl peptide - ENSP00000403211
Ensembl peptide - ENSP00000399955
Ensembl peptide - ENSP00000398620
Ensembl peptide - ENSP00000252725
Ensembl peptide - ENSP00000388802
Ensembl peptide - ENSP00000389631
NCBI entrez gene - 10095     See in Manteia.
OMIM - 604223
RefSeq - NM_005720
RefSeq - XM_006715825
RefSeq - XM_006715826
RefSeq Peptide - NP_005711
swissprot - C9JEY1
swissprot - C9JBJ7
swissprot - C9J6C8
swissprot - C9J4Z7
swissprot - C9K057
swissprot - F8VXW2
swissprot - F8WEB3
swissprot - O15143
swissprot - A4D275
swissprot - C9JTT6
swissprot - C9JQM8
swissprot - C9JM51
swissprot - C9JFG9
Ensembl - ENSG00000130429
  
Related genetic diseases (OMIM): 617718 - Platelet abnormalities with eosinophilia and immune-mediated inflammatory disease, 617718
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arpc1bENSDARG00000027063Danio rerio
 ARPC1BENSGALG00000032588Gallus gallus
 Arpc1bENSMUSG00000029622Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC004922.1ENSG0000028429280
ARPC1A / Q92747 / actin related protein 2/3 complex subunit 1AENSG0000024168567


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017383  Actin-related protein 2/3 complex subunit 1
 IPR017986  WD40-repeat-containing domain
 IPR030141  Actin-related protein 2/3 complex subunit 1B
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030833 regulation of actin filament polymerization IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0034314 Arp2/3 complex-mediated actin nucleation IEA
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0043627 response to estrogen IEA
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005885 Arp2/3 protein complex IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0036284 tubulobulbar complex IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0051015 actin filament binding IDA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr