ENSDARG00000027063


Danio rerio

Features
Gene ID: ENSDARG00000027063
  
Biological name :arpc1b
  
Synonyms : actin related protein 2/3 complex, subunit 1B / arpc1b
  
Possible biological names infered from orthology : O15143 / Q9WV32
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 40809011
Gene end: 40820612
  
Corresponding Affymetrix probe sets: Dr.7105.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000038520
Ensembl peptide - ENSDARP00000146922
NCBI entrez gene - 335474     See in Manteia.
swissprot - Q7T372
ZFIN ID - ZDB-GENE-030131-7414
Ensembl - ENSDARG00000027063
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARPC1BENSGALG00000032588Gallus gallus
 ARPC1BENSG00000130429Homo sapiens
 Arpc1bENSMUSG00000029622Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arpc1a / actin related protein 2/3 complex, subunit 1A / Q92747* / Q9R0Q6*ENSDARG0000000838368
zgc:86896ENSDARG0000009036960


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017383  Actin-related protein 2/3 complex subunit 1
 IPR017986  WD40-repeat-containing domain
 IPR030141  Actin-related protein 2/3 complex subunit 1B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030833 regulation of actin filament polymerization IEA
 biological_processGO:0034314 Arp2/3 complex-mediated actin nucleation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005885 Arp2/3 protein complex IBA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0051015 actin filament binding IBA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0005898 caudal hematopoietic tissue caudal hematopoietic tissue thromboblast decreased amount , abnormal
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 ZFA:0009323 thrombocyte thrombocyte decreased amount , abnormal
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 ZFA:0009350 pro-T cell pro-T cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr