ENSMUSG00000029622


Mus musculus

Features
Gene ID: ENSMUSG00000029622
  
Biological name :Arpc1b
  
Synonyms : Actin-related protein 2/3 complex subunit 1B / Arpc1b / Q9WV32
  
Possible biological names infered from orthology : O15143
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G2
Gene start: 145114215
Gene end: 145130705
  
Corresponding Affymetrix probe sets: 10527441 (MoGene1.0st)   10604763 (MoGene1.0st)   1416226_at (Mouse Genome 430 2.0 Array)   1416227_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122340
Ensembl peptide - ENSMUSP00000115022
Ensembl peptide - ENSMUSP00000082822
Ensembl peptide - ENSMUSP00000115515
Ensembl peptide - ENSMUSP00000143438
NCBI entrez gene - 11867     See in Manteia.
MGI - MGI:1343142
RefSeq - NM_023142
RefSeq Peptide - NP_075631
swissprot - Q9WV32
swissprot - D3Z6S0
swissprot - F6THG2
swissprot - F6VVE6
swissprot - Q91Z25
Ensembl - ENSMUSG00000029622
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arpc1bENSDARG00000027063Danio rerio
 ARPC1BENSGALG00000032588Gallus gallus
 ARPC1BENSG00000130429Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Arpc1a / Q9R0Q6 / Actin-related protein 2/3 complex subunit 1A ENSMUSG0000002962168


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017383  Actin-related protein 2/3 complex subunit 1
 IPR017986  WD40-repeat-containing domain
 IPR030141  Actin-related protein 2/3 complex subunit 1B
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030833 regulation of actin filament polymerization IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0034314 Arp2/3 complex-mediated actin nucleation IEA
 biological_processGO:0043627 response to estrogen IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005885 Arp2/3 protein complex IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0036284 tubulobulbar complex IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000150 abnormal rib morphology "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311]
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Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0004609 vertebral fusion "the union of one or more vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0004613 fusion of vertebral arches "improper union of the dorsal part of adjacent vertebra" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0010067 increased red blood cell distribution width "higher than normal coefficient of variance (reference range) of the red blood cell volume for an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", NCI:C64800 "NCI Thesaurus (Code C64800)"]
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Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0010088 decreased circulating fructosamine level "decrease in the concentration in the blood of total non enzymatic glycated proteins in the blood" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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