ENSG00000253309


Homo sapiens

Features
Gene ID: ENSG00000253309
  
Biological name :SERPINE3
  
Synonyms : A8MV23 / SERPINE3 / serpin family E member 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q14.3
Gene start: 51335773
Gene end: 51364735
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000428316
Ensembl peptide - ENSP00000441468
Ensembl peptide - ENSP00000430755
Ensembl peptide - ENSP00000427824
NCBI entrez gene - 647174     See in Manteia.
RefSeq - NM_001101320
RefSeq - XM_017020707
RefSeq Peptide - NP_001094790
swissprot - E5RG55
swissprot - A8MV23
Ensembl - ENSG00000253309
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B0UYL8ENSDARG00000057108Danio rerio
 SERPINE3ENSGALG00000017017Gallus gallus
 Serpine3ENSMUSG00000091155Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P07093 / SERPINE2 / serpin family E member 2ENSG0000013591929
P05121 / SERPINE1 / serpin family E member 1ENSG0000010636628
P01008 / SERPINC1 / serpin family C member 1ENSG0000011760127
Q99574 / SERPINI1 / serpin family I member 1ENSG0000016353626
O75830 / SERPINI2 / serpin family I member 2ENSG0000011420424
O75635 / SERPINB7 / serpin family B member 7ENSG0000016639622
Q96P63 / SERPINB12 / serpin family B member 12ENSG0000016663422
Q96P15 / SERPINB11 / serpin family B member 11 (gene/pseudogene)ENSG0000020607221
P50454 / SERPINH1 / serpin family H member 1ENSG0000014925720


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain
 IPR031172  Serpin E3
 IPR036186  Serpin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IBA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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