ENSG00000166634


Homo sapiens

Features
Gene ID: ENSG00000166634
  
Biological name :SERPINB12
  
Synonyms : Q96P63 / SERPINB12 / serpin family B member 12
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q21.33
Gene start: 63556160
Gene end: 63567011
  
Corresponding Affymetrix probe sets: 1553057_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000269491
Ensembl peptide - ENSP00000372218
NCBI entrez gene - 89777     See in Manteia.
OMIM - 615662
RefSeq - XM_017026067
RefSeq - NM_001307928
RefSeq - NM_080474
RefSeq - XM_011526246
RefSeq - XM_011526248
RefSeq - XM_011526249
RefSeq - XM_005266778
RefSeq Peptide - NP_536722
RefSeq Peptide - NP_001294857
swissprot - Q96P63
Ensembl - ENSG00000166634
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SERPINB12ENSGALG00000012872Gallus gallus
 Q9D7P9ENSMUSG00000059956Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O75635 / SERPINB7 / serpin family B member 7ENSG0000016639637
P01008 / SERPINC1 / serpin family C member 1ENSG0000011760133
Q96P15 / SERPINB11 / serpin family B member 11 (gene/pseudogene)ENSG0000020607232
O75830 / SERPINI2 / serpin family I member 2ENSG0000011420432
Q99574 / SERPINI1 / serpin family I member 1ENSG0000016353628
P07093 / SERPINE2 / serpin family E member 2ENSG0000013591927
P05121 / SERPINE1 / serpin family E member 1ENSG0000010636626
P50454 / SERPINH1 / serpin family H member 1ENSG0000014925726
A8MV23 / SERPINE3 / serpin family E member 3ENSG0000025330922


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain
 IPR036186  Serpin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IEA
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0042177 negative regulation of protein catabolic process NAS
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IMP
 molecular_functionGO:0019899 enzyme binding NAS
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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