ENSMUSG00000059956


Mus musculus

Features
Gene ID: ENSMUSG00000059956
  
Biological name :Serpinb12
  
Synonyms : Q9D7P9 / Serpin B12 / Serpinb12
  
Possible biological names infered from orthology : Q96P63 / serpin family B member 12
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: E2.1
Gene start: 106934449
Gene end: 106957080
  
Corresponding Affymetrix probe sets: 10349118 (MoGene1.0st)   1429297_at (Mouse Genome 430 2.0 Array)   1432173_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000080030
Ensembl peptide - ENSMUSP00000108344
NCBI entrez gene - 71869     See in Manteia.
MGI - MGI:1919119
RefSeq - NM_001199213
RefSeq - NM_027971
RefSeq Peptide - NP_001186142
RefSeq Peptide - NP_082247
swissprot - Q9D7P9
Ensembl - ENSMUSG00000059956
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SERPINB12ENSGALG00000012872Gallus gallus
 Q96P63ENSG00000166634Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9CQV3 / Serpinb11 / Serpin B11 / Q96P15* / serpin family B member 11 (gene/pseudogene)*ENSMUSG0000002632736
Q9D695 / Serpinb7 / Serpin B7 / O75635* / serpin family B member 7*ENSMUSG0000006700135
P32261 / Serpinc1 / serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 / P01008* / serpin family C member 1*ENSMUSG0000002671532
Q9JK88 / Serpini2 / serine (or cysteine) peptidase inhibitor, clade I, member 2 / O75830* / serpin family I member 2*ENSMUSG0000003413929
O35684 / Serpini1 / serine (or cysteine) peptidase inhibitor, clade I, member 1 / Q99574* / serpin family I member 1*ENSMUSG0000002783427
Q07235 / Serpine2 / serine (or cysteine) peptidase inhibitor, clade E, member 2 / P07093* / serpin family E member 2*ENSMUSG0000002624927
P19324 / Serpinh1 / Serpin H1 / P50454* / serpin family H member 1*ENSMUSG0000007043626
Serpine1 / serine (or cysteine) peptidase inhibitor, clade E, member 1 / P05121* / serpin family E member 1*ENSMUSG0000003741123
Serpine3 / serpin family E member 3 / A8MV23*ENSMUSG0000009115521


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain
 IPR036186  Serpin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IMP
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IBA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001410 head bobbing "compulsive up and down movement of the head" [J:17123]
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Allelic Composition: Scribtm1b(NCOM)Mfgc/Scribtm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Scribtm1a(NCOM)Mfgc/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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