ENSG00000258643


Homo sapiens

Features
Gene ID: ENSG00000258643
  
Biological name :BCL2L2-PABPN1
  
Synonyms : BCL2L2-PABPN1 / BCL2L2-PABPN1 readthrough / Q92843
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q11.2
Gene start: 23306835
Gene end: 23325369
  
Corresponding Affymetrix probe sets: 201544_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451320
Ensembl peptide - ENSP00000452479
NCBI entrez gene - 100529063     See in Manteia.
RefSeq - NM_001199864
RefSeq Peptide - NP_001186793
swissprot - Q92843
Ensembl - ENSG00000258643
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pabpn1ENSDARG00000045373Danio rerio
 Gm20521ENSMUSG00000092232Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PABPN1 / Q86U42 / poly(A) binding protein nuclear 1ENSG0000010083664
A6NDY0 / PABPN1L / poly(A) binding protein nuclear 1 like, cytoplasmicENSG0000020502232


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR002475  Bcl2-like
 IPR003093  Apoptosis regulator, Bcl-2 protein, BH4
 IPR013280  Apoptosis regulator, Bcl-W
 IPR020717  Apoptosis regulator, Bcl-2, BH1 motif, conserved site
 IPR020731  Apoptosis regulator, Bcl-2, BH4 motif, conserved site
 IPR026298  Blc2 family
 IPR034911  Polyadenylate-binding protein 2
 IPR035979  RNA-binding domain superfamily
 IPR036834  Blc2-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007283 spermatogenesis TAS
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IBA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IBA
 biological_processGO:1904247 positive regulation of polynucleotide adenylyltransferase activity IEA
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IBA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0097136 Bcl-2 family protein complex IMP
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IBA
 molecular_functionGO:0046982 protein heterodimerization activity IBA
 molecular_functionGO:0097718 disordered domain specific binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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