ENSG00000258992


Homo sapiens

Features
Gene ID: ENSG00000258992
  
Biological name :TSPY1
  
Synonyms : Q01534 / testis specific protein, Y-linked 1 / TSPY1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: Y
Strand: 1
Band: p11.2
Gene start: 9466955
Gene end: 9469748
  
Corresponding Affymetrix probe sets: 207918_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000389324
Ensembl peptide - ENSP00000403304
NCBI entrez gene - 7258     See in Manteia.
OMIM - 480100
RefSeq - XM_017030064
RefSeq - NM_001197242
RefSeq - NM_001320964
RefSeq - NM_003308
RefSeq Peptide - NP_001307893
RefSeq Peptide - NP_003299
RefSeq Peptide - NP_001184171
swissprot - Q01534
Ensembl - ENSG00000258992
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tspyENSDARG00000005015Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TSPY3 / P0CV98 / testis specific protein, Y-linked 3ENSG0000022892790
TSPY10 / testis specific protein, Y-linked 10ENSG0000023642490
TSPY4 / P0CV99 / P0CW01 / testis specific protein, Y-linked 4ENSG0000023380390
TSPY2 / A6NKD2 / testis specific protein, Y-linked 2ENSG0000016875789
TSPY8 / P0CW00 / testis specific protein, Y-linked 8ENSG0000022954989
Q9H0U9 / TSPYL1 / TSPY like 1ENSG0000018924135
Q9UJ04 / TSPYL4 / TSPY like 4ENSG0000018718931
Q8N831 / TSPYL6 / TSPY like 6ENSG0000017802130
Q9H2G4 / TSPYL2 / TSPY like 2ENSG0000018420529
Q86VY4 / TSPYL5 / TSPY like 5ENSG0000018054328
SET / Q01105 / SET nuclear proto-oncogeneENSG0000011933524
P0DME0 / SETSIP / SET-like proteinENSG0000023066723


Protein motifs (from Interpro)
Interpro ID Name
 IPR002164  Nucleosome assembly protein (NAP)
 IPR037231  NAP-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006334 nucleosome assembly IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis TAS
 biological_processGO:0007506 gonadal mesoderm development IEA
 biological_processGO:0007548 sex differentiation TAS
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0000028 Cryptorchidism "Absence of one or both testes from the scrotum owing to failure of the testis or testes to descend through the inguinal canal to the testis." [HPO:curators]
Show

 HP:0000798 Oligospermia 
Show

 HP:0003251 Male infertility 
Show

 HP:0008734 Decreased testicular size 
Show

 HP:0011961 Non-obstructive azoospermia "Absence of any measurable level of sperm in his semen, resulting from a defect in the production of spermatozoa in the testes. Can be differentiated from obstructive azoospermia on the basis of testicular biopsy." [HPO:probinson, pmid:20514278]
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr