ENSG00000119335


Homo sapiens

Features
Gene ID: ENSG00000119335
  
Biological name :SET
  
Synonyms : Q01105 / SET / SET nuclear proto-oncogene
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q34.11
Gene start: 128683424
Gene end: 128696400
  
Corresponding Affymetrix probe sets: 200630_x_at (Human Genome U133 Plus 2.0 Array)   200631_s_at (Human Genome U133 Plus 2.0 Array)   210231_x_at (Human Genome U133 Plus 2.0 Array)   213047_x_at (Human Genome U133 Plus 2.0 Array)   215780_s_at (Human Genome U133 Plus 2.0 Array)   40189_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361773
Ensembl peptide - ENSP00000361771
Ensembl peptide - ENSP00000361777
Ensembl peptide - ENSP00000410806
Ensembl peptide - ENSP00000387321
Ensembl peptide - ENSP00000318012
NCBI entrez gene - 6418     See in Manteia.
OMIM - 600960
RefSeq - XM_017015016
RefSeq - NM_001122821
RefSeq - NM_001248000
RefSeq - NM_001248001
RefSeq - NM_003011
RefSeq - XM_017015013
RefSeq - XM_017015014
RefSeq - XM_017015015
RefSeq Peptide - NP_001116293
RefSeq Peptide - NP_001234930
RefSeq Peptide - NP_003002
RefSeq Peptide - NP_001234929
swissprot - A0A024R895
swissprot - Q01105
swissprot - Q5VXV3
swissprot - B2REB7
swissprot - A0A0C4DFV9
Ensembl - ENSG00000119335
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 setaENSDARG00000031495Danio rerio
 setbENSDARG00000003920Danio rerio
 SETENSGALG00000004701Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P0DME0 / SETSIP / SET-like proteinENSG0000023066795
Q9H2G4 / TSPYL2 / TSPY like 2ENSG0000018420536
Q9H0U9 / TSPYL1 / TSPY like 1ENSG0000018924131
Q9UJ04 / TSPYL4 / TSPY like 4ENSG0000018718931
Q8N831 / TSPYL6 / TSPY like 6ENSG0000017802130
Q86VY4 / TSPYL5 / TSPY like 5ENSG0000018054330
TSPY1 / Q01534 / testis specific protein, Y-linked 1ENSG0000025899226
TSPY2 / A6NKD2 / testis specific protein, Y-linked 2ENSG0000016875723
TSPY4 / P0CV99 / P0CW01 / testis specific protein, Y-linked 4ENSG0000023380323
TSPY3 / P0CV98 / testis specific protein, Y-linked 3ENSG0000022892723
TSPY8 / P0CW00 / testis specific protein, Y-linked 8ENSG0000022954923
TSPY10 / testis specific protein, Y-linked 10ENSG0000023642423


Protein motifs (from Interpro)
Interpro ID Name
 IPR002164  Nucleosome assembly protein (NAP)
 IPR037231  NAP-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication TAS
 biological_processGO:0006334 nucleosome assembly IEA
 biological_processGO:0006337 nucleosome disassembly TAS
 biological_processGO:0006913 nucleocytoplasmic transport NAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0035067 negative regulation of histone acetylation TAS
 biological_processGO:0043488 regulation of mRNA stability TAS
 biological_processGO:0043524 negative regulation of neuron apoptotic process IGI
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005811 lipid droplet IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004864 protein phosphatase inhibitor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019888 protein phosphatase regulator activity TAS
 molecular_functionGO:0042393 histone binding TAS


Pathways (from Reactome)
Pathway description
Condensation of Prophase Chromosomes
HuR (ELAVL1) binds and stabilizes mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000147316 MCPH1 / Q8NEM0 / microcephalin 1  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr