ENSG00000277443


Homo sapiens

Features
Gene ID: ENSG00000277443
  
Biological name :MARCKS
  
Synonyms : MARCKS / myristoylated alanine rich protein kinase C substrate / P29966
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q21
Gene start: 113857362
Gene end: 113863471
  
Corresponding Affymetrix probe sets: 201668_x_at (Human Genome U133 Plus 2.0 Array)   201669_s_at (Human Genome U133 Plus 2.0 Array)   201670_s_at (Human Genome U133 Plus 2.0 Array)   213002_at (Human Genome U133 Plus 2.0 Array)   225897_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478061
NCBI entrez gene - 4082     See in Manteia.
OMIM - 177061
RefSeq - NM_002356
RefSeq Peptide - NP_002347
swissprot - P29966
Ensembl - ENSG00000277443
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 marcksaENSDARG00000004049Danio rerio
 marcksbENSDARG00000008803Danio rerio
 MARCKSENSGALG00000037726Gallus gallus
 MarcksENSMUSG00000069662Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002101  Myristoylated alanine-rich C-kinase substrate MARCKS


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0050796 regulation of insulin secretion TAS
 biological_processGO:0051017 actin filament bundle assembly IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0051764 actin crosslink formation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0015629 actin cytoskeleton TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032432 actin filament bundle IEA
 cellular_componentGO:0042585 germinal vesicle IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005080 protein kinase C binding IEA
 molecular_functionGO:0005516 calmodulin binding TAS
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Acetylcholine regulates insulin secretion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000154229 PRKCA / P17252 / protein kinase C alpha  / reaction






 

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