ENSG00000280969


Homo sapiens

Features
Gene ID: ENSG00000280969
  
Biological name :RPS4Y2
  
Synonyms : Q8TD47 / ribosomal protein S4, Y-linked 2 / RPS4Y2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: Y
Strand: 1
Band: q11.223
Gene start: 20756164
Gene end: 20781032
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000486252
NCBI entrez gene - 140032     See in Manteia.
OMIM - 400030
RefSeq - NM_001039567
RefSeq Peptide - NP_001034656
swissprot - Q8TD47
Ensembl - ENSG00000280969
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rps4xENSDARG00000014690Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P22090 / RPS4Y1 / ribosomal protein S4, Y-linked 1ENSG0000012982494
RPS4X / P62701 / ribosomal protein S4, X-linkedENSG0000019803492


Protein motifs (from Interpro)
Interpro ID Name
 IPR000876  Ribosomal protein S4e
 IPR002942  RNA-binding S4 domain
 IPR005824  KOW
 IPR013843  Ribosomal protein S4e, N-terminal
 IPR013845  Ribosomal protein S4e, central region
 IPR018199  Ribosomal protein S4e, N-terminal, conserved site
 IPR032277  40S ribosomal protein S4, C-terminal domain
 IPR036986  RNA-binding S4 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IBA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0022627 cytosolic small ribosomal subunit IBA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0003735 structural constituent of ribosome IBA
 molecular_functionGO:0019843 rRNA binding IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0000027 Azoospermia 
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 HP:0001450 Y-linked inheritance "A mode of inheritance that is observed for traits related to a gene encoded on the Y chromosome." [HPO:curators]
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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