ENSDARG00000014690


Danio rerio

Features
Gene ID: ENSDARG00000014690
  
Biological name :rps4x
  
Synonyms : Q642H9 / ribosomal protein S4, X-linked / rps4x
  
Possible biological names infered from orthology : Gm15013 / P22090 / P62701 / P62702 / Q8TD47 / ribosomal protein S4, Y-linked 1 / ribosomal protein S4, Y-linked 2 / RPS4Y1 / RPS4Y2
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 51633815
Gene end: 51639699
  
Corresponding Affymetrix probe sets: Dr.4412.4.S1_at (Zebrafish Array)   NM_001005589_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000108089
NCBI entrez gene - 449547     See in Manteia.
RefSeq - NM_001005589
RefSeq Peptide - NP_001005589
swissprot - Q642H9
ZFIN ID - ZDB-GENE-040927-19
Ensembl - ENSDARG00000014690
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPS4XENSGALG00000004831Gallus gallus
 P22090ENSG00000129824Homo sapiens
 Q8TD47ENSG00000280969Homo sapiens
 RPS4XENSG00000198034Homo sapiens
 Gm15013ENSMUSG00000098559Mus musculus
 Rps4xENSMUSG00000031320Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000876  Ribosomal protein S4e
 IPR002942  RNA-binding S4 domain
 IPR005824  KOW
 IPR013843  Ribosomal protein S4e, N-terminal
 IPR013845  Ribosomal protein S4e, central region
 IPR032277  40S ribosomal protein S4, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IBA
 biological_processGO:0007420 brain development IMP
 biological_processGO:0043009 chordate embryonic development IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0022627 cytosolic small ribosomal subunit IBA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0003735 structural constituent of ribosome IBA
 molecular_functionGO:0019843 rRNA binding IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
SRP-dependent cotranslational protein targeting to membrane
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000006 ball ball increased size , abnormal
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 ZFA:0000029 hindbrain hindbrain opaque , abnormal
hindbrain undulate , abnormal
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 ZFA:0000035 lens lens decreased size , abnormal
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 ZFA:0000079 telencephalon telencephalon decreased size , abnormal
telencephalon hypoplastic , abnormal
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 ZFA:0000100 cerebellum cerebellum aplastic , abnormal
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 ZFA:0000106 extension extension decreased thickness , abnormal
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 ZFA:0000108 fin fin aplastic , abnormal
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 ZFA:0000109 forebrain forebrain protruding , abnormal
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 ZFA:0000128 midbrain midbrain aplastic , abnormal
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 ZFA:0000138 otic placode otic placode decreased size , abnormal
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 ZFA:0000152 retina retina decreased size , abnormal
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 ZFA:0000445 optic tectum optic tectum increased size , abnormal
optic tectum opaque , abnormal
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 ZFA:0001114 head head flat , abnormal
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 ZFA:0001115 trunk trunk undulate , abnormal
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 ZFA:0001117 post-vent region post-vent region bent , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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