ENSG00000284969


Homo sapiens

Features
Gene ID: ENSG00000284969
  
Biological name :AL049629.2
  
Synonyms : AL049629.2 / CD59 glycoprotein / P13987
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p13
Gene start: 33698261
Gene end: 33722467
  
Corresponding Affymetrix probe sets: 200983_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000437122
Ensembl peptide - ENSP00000432362
Ensembl peptide - ENSP00000435179
Ensembl peptide - ENSP00000436497
swissprot - E9PNW4
swissprot - Q6FHM9
swissprot - E9PR17
swissprot - H0YET2
swissprot - P13987
Ensembl - ENSG00000284969
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000040371Gallus gallus
 Cd59aENSMUSG00000032679Mus musculus
 Cd59bENSMUSG00000068686Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD59 / P13987 / CD59 molecule (CD59 blood group)ENSG00000085063100


Protein motifs (from Interpro)
Interpro ID Name
 IPR016054  Ly-6 antigen/uPA receptor-like
 IPR018363  CD59 antigen, conserved site
 IPR027101  CD59 glycoprotein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001775 cell activation IBA
 biological_processGO:0001971 negative regulation of activation of membrane attack complex IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0030449 regulation of complement activation IBA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0048208 COPII vesicle coating TAS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005886 plasma membrane NAS
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0012507 ER to Golgi transport vesicle membrane TAS
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0030133 transport vesicle TAS
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0031362 anchored component of external side of plasma membrane IDA
 cellular_componentGO:0031982 vesicle HDA
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane TAS
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070821 tertiary granule membrane TAS
 molecular_functionGO:0001848 complement binding IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
Cargo concentration in the ER
Neutrophil degranulation
COPI-mediated anterograde transport
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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