ENSGALG00000000235


Gallus gallus

Features
Gene ID: ENSGALG00000000235
  
Biological name :PPP2R2A
  
Synonyms : PPP2R2A / protein phosphatase 2 regulatory subunit Balpha
  
Possible biological names infered from orthology : P63151 / protein phosphatase 2, regulatory subunit B, alpha / Q6P1F6
  
Species: Gallus gallus
  
Chr. number: 22
Strand: -1
Band:
Gene start: 551092
Gene end: 584895
  
Corresponding Affymetrix probe sets: Gga.11018.1.S1_at (Chicken Array)   Gga.7.1.S1_at (Chicken Array)   Gga.9510.1.S1_at (Chicken Array)   Gga.9510.2.S1_at (Chicken Array)   GgaAffx.11793.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056779
Ensembl peptide - ENSGALP00000030863
Ensembl peptide - ENSGALP00000051137
NCBI entrez gene - 419523     See in Manteia.
RefSeq - XM_015297315
RefSeq - NM_001030886
RefSeq - XM_015297313
RefSeq - XM_015297314
RefSeq Peptide - NP_001026057
swissprot - Q5ZLP4
swissprot - F1NBJ2
swissprot - A0A1D5PED5
Ensembl - ENSGALG00000000235
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp2r2aaENSDARG00000021996Danio rerio
 ppp2r2abENSDARG00000006624Danio rerio
 P63151ENSG00000221914Homo sapiens
 Q6P1F6ENSMUSG00000022052Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPP2R2D / serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform / Q66LE6* / Q925E7* / protein phosphatase 2 regulatory subunit Bdelta* / protein phosphatase 2, ...ENSGALG0000001047188
PPP2R2B / protein phosphatase 2 regulatory subunit Bbeta / Q00005* / Q6ZWR4* / protein phosphatase 2, regulatory subunit B, beta*ENSGALG0000000756583
PPP2R2C / protein phosphatase 2 regulatory subunit Bgamma / Q8BG02* / Q9Y2T4* / protein phosphatase 2, regulatory subunit B, gamma*ENSGALG0000001553179


Protein motifs (from Interpro)
Interpro ID Name
 IPR000009  Protein phosphatase 2A regulatory subunit PR55
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR018067  Protein phosphatase 2A regulatory subunit PR55, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IBA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0032502 developmental process IBA
 biological_processGO:0043278 response to morphine IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0070262 peptidyl-serine dephosphorylation IBA
 cellular_componentGO:0000159 protein phosphatase type 2A complex IBA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity IBA


Pathways (from Reactome)
Pathway description
Initiation of Nuclear Envelope Reformation
Cyclin D associated events in G1
Cyclin A/B1/B2 associated events during G2/M transition
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006462 PPP2CA / protein phosphatase 2 catalytic subunit alpha / P63330* / P67775* / Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform *  / complex






 

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