ENSGALG00000000498


Gallus gallus

Features
Gene ID: ENSGALG00000000498
  
Biological name :ACE
  
Synonyms : ACE
  
Possible biological names infered from orthology : AC113554.1 / Ace3 / angiotensin I converting enzyme / angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 / angiotensin I converting enzyme (peptidyl-dipeptidase A) 3 / D0G895 / P09470 / P12821
  
Species: Gallus gallus
  
Chr. number: 27
Strand: 1
Band:
Gene start: 2830975
Gene end: 2847223
  
Corresponding Affymetrix probe sets: Gga.3781.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000039731
NCBI entrez gene - 419953     See in Manteia.
RefSeq - NM_001167732
RefSeq Peptide - NP_001161204
swissprot - F1NYM0
Ensembl - ENSGALG00000000498
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aceENSDARG00000079166Danio rerio
 AC113554.1ENSG00000264813Homo sapiens
 ACEENSG00000159640Homo sapiens
 AceENSMUSG00000020681Mus musculus
 Ace3ENSMUSG00000101605Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACE2 / angiotensin I converting enzyme 2 / Q8R0I0* / Q9BYF1* / angiotensin I converting enzyme (peptidyl-dipeptidase A) 2*ENSGALG0000001655421
CLTRN / collectrin, amino acid transport regulator / Q9ESG4* / Q9HBJ8* / Tmem27* / Collectrin *ENSGALG000000291681


Protein motifs (from Interpro)
Interpro ID Name
 IPR001548  Peptidase M2, peptidyl-dipeptidase A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development ISA
 biological_processGO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin ISA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0042447 hormone catabolic process ISA
 biological_processGO:0043171 peptide catabolic process ISA
 biological_processGO:0050435 amyloid-beta metabolic process ISA
 biological_processGO:0050482 arachidonic acid secretion ISA
 biological_processGO:0060177 regulation of angiotensin metabolic process ISA
 biological_processGO:0060319 primitive erythrocyte differentiation IMP
 cellular_componentGO:0005615 extracellular space ISA
 cellular_componentGO:0005764 lysosome ISA
 cellular_componentGO:0005768 endosome ISA
 cellular_componentGO:0005886 plasma membrane ISA
 cellular_componentGO:0009897 external side of plasma membrane ISA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IDA
 cellular_componentGO:0070062 extracellular exosome ISA
 molecular_functionGO:0003779 actin binding ISS
 molecular_functionGO:0004175 endopeptidase activity ISA
 molecular_functionGO:0004180 carboxypeptidase activity IEA
 molecular_functionGO:0008144 drug binding ISA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity ISA
 molecular_functionGO:0008238 exopeptidase activity ISA
 molecular_functionGO:0008239 dipeptidyl-peptidase activity IDA
 molecular_functionGO:0008240 tripeptidyl-peptidase activity ISA
 molecular_functionGO:0008241 peptidyl-dipeptidase activity ISA
 molecular_functionGO:0008270 zinc ion binding ISA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0031404 chloride ion binding ISA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding ISA
 molecular_functionGO:0031711 bradykinin receptor binding ISA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051019 mitogen-activated protein kinase binding ISA
 molecular_functionGO:0070573 metallodipeptidase activity ISS


Pathways (from Reactome)
Pathway description
Metabolism of Angiotensinogen to Angiotensins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000011117 AGT / angiotensinogen / P01019*  / reaction






 

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