ENSGALG00000011117


Gallus gallus

Features
Gene ID: ENSGALG00000011117
  
Biological name :AGT
  
Synonyms : AGT / angiotensinogen
  
Possible biological names infered from orthology : P01019
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 40594171
Gene end: 40606054
  
Corresponding Affymetrix probe sets: Gga.12910.1.S1_at (Chicken Array)   Gga.2555.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018089
NCBI entrez gene - 421543     See in Manteia.
RefSeq - XM_004935493
RefSeq - XM_004935494
RefSeq - XM_419584
swissprot - F1NDH2
Ensembl - ENSGALG00000011117
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 agtENSDARG00000016412Danio rerio
 AGTENSG00000135744Homo sapiens
 AgtENSMUSG00000031980Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR000227  Angiotensinogen
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0003014 renal system process IEA
 biological_processGO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0010536 positive regulation of activation of Janus kinase activity IEA
 biological_processGO:0010595 positive regulation of endothelial cell migration IEA
 biological_processGO:0010873 positive regulation of cholesterol esterification IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0032270 positive regulation of cellular protein metabolic process IEA
 biological_processGO:0045742 positive regulation of epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway IEA
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity IEA
 biological_processGO:0090190 positive regulation of branching involved in ureteric bud morphogenesis IEA
 biological_processGO:1901201 regulation of extracellular matrix assembly IEA
 biological_processGO:1903598 positive regulation of gap junction assembly IEA
 biological_processGO:1903779 regulation of cardiac conduction IEA
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0031702 type 1 angiotensin receptor binding IEA
 molecular_functionGO:0031703 type 2 angiotensin receptor binding IEA


Pathways (from Reactome)
Pathway description
Metabolism of Angiotensinogen to Angiotensins
Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000005936 AGTR2 / angiotensin II receptor type 2 / P35374* / P50052* / Type-2 angiotensin II receptor *  / reaction / complex
 ENSGALG00000007462 CTSZ / cathepsin Z / Q9UBR2* / Q9WUU7*  / reaction
 ENSGALG00000016554 ACE2 / angiotensin I converting enzyme 2 / Q8R0I0* / Q9BYF1* / angiotensin I converting enzyme (peptidyl-dipeptidase A) 2*  / reaction
 ENSGALG00000038512 AGTR1 / P79785 / Type-1 angiotensin II receptor / P30556* / P29755* / Agtr1a* / Agtr1b* / P29754* / angiotensin II receptor type 1* / Type-1A angiotensin II receptor * / Type-1B angiotensi...  / complex / reaction
 ENSGALG00000010331 MME / membrane metalloendopeptidase / P08473* / Q61391* / Neprilysin *  / reaction
 ENSGALG00000000498 ACE / Ace3* / D0G895* / P12821* / P09470* / AC113554.1* / angiotensin I converting enzyme* / angiotensin I converting enzyme (peptidyl-dipeptidase A) 3* / angiotensin I converting enzyme (p...  / reaction






 

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