ENSDARG00000016412


Danio rerio

Features
Gene ID: ENSDARG00000016412
  
Biological name :agt
  
Synonyms : agt / angiotensinogen
  
Possible biological names infered from orthology : P01019
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 23988442
Gene end: 23995876
  
Corresponding Affymetrix probe sets: Dr.3585.1.S1_at (Zebrafish Array)   NM_198063_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000017923
NCBI entrez gene - 322485     See in Manteia.
RefSeq - NM_198063
RefSeq Peptide - NP_932329
swissprot - Q8JH29
ZFIN ID - ZDB-GENE-030131-1205
Ensembl - ENSDARG00000016412
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AGTENSGALG00000011117Gallus gallus
 AGTENSG00000135744Homo sapiens
 AgtENSMUSG00000031980Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR000227  Angiotensinogen
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain
 IPR033834  Angiotensinogen serpin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
Metabolism of Angiotensinogen to Angiotensins
Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000016918 ace2 / angiotensin I converting enzyme 2 / Q8R0I0* / Q9BYF1* / angiotensin I converting enzyme (peptidyl-dipeptidase A) 2*  / reaction
 ENSDARG00000045443 agtr1b / angiotensin II receptor, type 1b / AGTR1* / P29755* / Agtr1a* / P29754* / P30556* / angiotensin II receptor type 1* / Type-1B angiotensin II receptor * / Type-1A angiotensin II receptor *  / reaction / complex
 ENSDARG00000018616 agtr1a / angiotensin II receptor, type 1a / AGTR1* / P29755* / Agtr1b* / P29754* / P30556* / angiotensin II receptor type 1* / Type-1B angiotensin II receptor * / Type-1A angiotensin II receptor *  / complex / reaction
 ENSDARG00000045442 cpb1 / carboxypeptidase B1 (tissue) / CPA3* / P15089* / P15086* / P15088* / carboxypeptidase A3* / carboxypeptidase B1* / Mast cell carboxypeptidase A *  / reaction
 ENSDARG00000057064 enpep / glutamyl aminopeptidase / P16406* / Q07075*  / reaction
 ENSDARG00000079166 ace / angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 / Ace3* / P12821* / P09470* / D0G895* / AC113554.1* / angiotensin I converting enzyme* / angiotensin I converting enzyme (pe...  / reaction






 

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