ENSDARG00000057064


Danio rerio

Features
Gene ID: ENSDARG00000057064
  
Biological name :enpep
  
Synonyms : enpep / glutamyl aminopeptidase
  
Possible biological names infered from orthology : P16406 / Q07075
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 12543634
Gene end: 12581388
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000074107
NCBI entrez gene - 504088     See in Manteia.
RefSeq - NM_001199731
RefSeq Peptide - NP_001186660
swissprot - B8JIB4
ZFIN ID - ZDB-GENE-050309-218
Ensembl - ENSDARG00000057064
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENPEPENSGALG00000031410Gallus gallus
 ENPEPENSG00000138792Homo sapiens
 EnpepENSMUSG00000028024Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
anpepb / alanyl (membrane) aminopeptidase b / ANPEP* / P97449* / P15144* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000010387833
si:ch211-147g22.5 / ANPEP* / P15144* / P97449* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000009728532
si:ch211-106j24.1 / ANPEP* / P15144* / P97449* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000003680931
erap2 / endoplasmic reticulum aminopeptidase 2 / Q6P179*ENSDARG0000009861831
erap1a / endoplasmic reticulum aminopeptidase 1a / ERAP1* / Q9EQH2* / Q9NZ08* / endoplasmic reticulum aminopeptidase 1*ENSDARG0000001302431
lnpep / leucyl/cystinyl aminopeptidase / Q9UIQ6* / leucyl and cystinyl aminopeptidase*ENSDARG0000010039430
ANPEP / si:ch211-276a23.5 / P15144* / P97449* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000008970630
erap1b / endoplasmic reticulum aminopeptidase 1b / ERAP1* / Q9EQH2* / Q9NZ08* / endoplasmic reticulum aminopeptidase 1*ENSDARG0000002185930
npepps / aminopeptidase puromycin sensitive / P55786* / Q11011* / Puromycin-sensitive aminopeptidase *ENSDARG0000004494329
anpepa / alanyl (membrane) aminopeptidase aENSDARG0000004108328
trhde.2 / trhde.1 / thyrotropin releasing hormone degrading enzyme, tandem duplicate 2 / TRHDE* / Q8K093* / Q9UKU6* / thyrotropin releasing hormone degrading enzyme* / Thyrotropin-releasing...ENSDARG0000011183728
trhde.2 / trhde.1 / thyrotropin releasing hormone degrading enzyme, tandem duplicate 1 / TRHDE* / Q8K093* / Q9UKU6* / thyrotropin releasing hormone degrading enzyme* / Thyrotropin-releasing...ENSDARG0000010935828


Protein motifs (from Interpro)
Interpro ID Name
 IPR001930  Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
 IPR014782  Peptidase M1, membrane alanine aminopeptidase, N-terminal
 IPR024571  ERAP1-like C-terminal domain
 IPR033508  Aminopeptidase A
 IPR034016  Aminopeptidase N-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002003 angiotensin maturation IEA
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070006 metalloaminopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of Angiotensinogen to Angiotensins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000016412 agt / angiotensinogen / P01019*  / reaction
 ENSDARG00000057064 enpep / glutamyl aminopeptidase / P16406* / Q07075*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr