ENSGALG00000031410


Gallus gallus

Features
Gene ID: ENSGALG00000031410
  
Biological name :ENPEP
  
Synonyms : ENPEP / glutamyl aminopeptidase
  
Possible biological names infered from orthology : P16406 / Q07075
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 58197816
Gene end: 58231230
  
Corresponding Affymetrix probe sets: Gga.10115.1.S1_s_at (Chicken Array)   GgaAffx.23788.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049914
NCBI entrez gene - 428771     See in Manteia.
RefSeq - XM_426327
swissprot - A0A1D5PAZ7
Ensembl - ENSGALG00000031410
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 enpepENSDARG00000057064Danio rerio
 ENPEPENSG00000138792Homo sapiens
 EnpepENSMUSG00000028024Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ANPEP / O57579 / Aminopeptidase Ey / P97449* / P15144* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSGALG0000002750133
LNPEP / leucyl and cystinyl aminopeptidase / Q8C129* / Q9UIQ6* / Leucyl-cystinyl aminopeptidase *ENSGALG0000001530132
ERAP1 / endoplasmic reticulum aminopeptidase 1 / Q9EQH2* / Q9NZ08*ENSGALG0000001468432
TRHDE / thyrotropin releasing hormone degrading enzyme / Q8K093* / Q9UKU6* / Thyrotropin-releasing hormone-degrading ectoenzyme *ENSGALG0000001020031
LVRN / laeverin / Q6Q4G3*ENSGALG0000000231828
NPEPPS / aminopeptidase puromycin sensitive / P55786* / Q11011* / Puromycin-sensitive aminopeptidase *ENSGALG0000003133219


Protein motifs (from Interpro)
Interpro ID Name
 IPR001930  Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
 IPR014782  Peptidase M1, membrane alanine aminopeptidase, N-terminal
 IPR024571  ERAP1-like C-terminal domain
 IPR033508  Aminopeptidase A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0002003 angiotensin maturation IEA
 biological_processGO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0032835 glomerulus development IEA
 cellular_componentGO:0005903 brush border IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045177 apical part of cell IEA
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070006 metalloaminopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of Angiotensinogen to Angiotensins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr