ENSGALG00000015301


Gallus gallus

Features
Gene ID: ENSGALG00000015301
  
Biological name :LNPEP
  
Synonyms : leucyl and cystinyl aminopeptidase / LNPEP
  
Possible biological names infered from orthology : Leucyl-cystinyl aminopeptidase / Q8C129 / Q9UIQ6
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 51602732
Gene end: 51651196
  
Corresponding Affymetrix probe sets: GgaAffx.9750.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053599
Ensembl peptide - ENSGALP00000024648
NCBI entrez gene - 427279     See in Manteia.
RefSeq - XM_424862
RefSeq - XM_015280478
RefSeq - XM_015280479
RefSeq - XM_015280476
RefSeq - XM_015280477
swissprot - F1NNE7
swissprot - A0A1D5PL84
Ensembl - ENSGALG00000015301
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lnpepENSDARG00000100394Danio rerio
 LNPEPENSG00000113441Homo sapiens
 LnpepENSMUSG00000023845Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ERAP1 / endoplasmic reticulum aminopeptidase 1 / Q9EQH2* / Q9NZ08*ENSGALG0000001468442
ENPEP / glutamyl aminopeptidase / P16406* / Q07075*ENSGALG0000003141029
ANPEP / O57579 / Aminopeptidase Ey / P97449* / P15144* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSGALG0000002750127
TRHDE / thyrotropin releasing hormone degrading enzyme / Q8K093* / Q9UKU6* / Thyrotropin-releasing hormone-degrading ectoenzyme *ENSGALG0000001020027
LVRN / laeverin / Q6Q4G3*ENSGALG0000000231825
NPEPPS / aminopeptidase puromycin sensitive / P55786* / Q11011* / Puromycin-sensitive aminopeptidase *ENSGALG0000003133216


Protein motifs (from Interpro)
Interpro ID Name
 IPR001930  Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
 IPR014782  Peptidase M1, membrane alanine aminopeptidase, N-terminal
 IPR024571  ERAP1-like C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0008217 regulation of blood pressure IBA
 biological_processGO:0030163 protein catabolic process IEA
 biological_processGO:0043171 peptide catabolic process IBA
 biological_processGO:0060395 SMAD protein signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0042277 peptide binding IBA
 molecular_functionGO:0070006 metalloaminopeptidase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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