ENSDARG00000044943


Danio rerio

Features
Gene ID: ENSDARG00000044943
  
Biological name :npepps
  
Synonyms : aminopeptidase puromycin sensitive / npepps
  
Possible biological names infered from orthology : P55786 / Puromycin-sensitive aminopeptidase / Q11011
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 12108355
Gene end: 12158412
  
Corresponding Affymetrix probe sets: Dr.12473.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000122475
NCBI entrez gene - 407726     See in Manteia.
RefSeq - NM_001164027
RefSeq Peptide - NP_001157499
swissprot - F1QRM9
ZFIN ID - ZDB-GENE-060524-3
Ensembl - ENSDARG00000044943
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NPEPPSENSGALG00000031332Gallus gallus
 NPEPPSENSG00000141279Homo sapiens
 NpeppsENSMUSG00000001441Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lnpep / leucyl/cystinyl aminopeptidase / Q9UIQ6* / leucyl and cystinyl aminopeptidase*ENSDARG0000010039431
anpepb / alanyl (membrane) aminopeptidase b / ANPEP* / P97449* / P15144* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000010387831
erap1a / endoplasmic reticulum aminopeptidase 1a / ERAP1* / Q9EQH2* / Q9NZ08* / endoplasmic reticulum aminopeptidase 1*ENSDARG0000001302430
erap2 / endoplasmic reticulum aminopeptidase 2 / Q6P179*ENSDARG0000009861830
si:ch211-147g22.5 / ANPEP* / P15144* / P97449* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000009728529
enpep / glutamyl aminopeptidase / P16406* / Q07075*ENSDARG0000005706429
erap1b / endoplasmic reticulum aminopeptidase 1b / ERAP1* / Q9EQH2* / Q9NZ08* / endoplasmic reticulum aminopeptidase 1*ENSDARG0000002185929
si:ch211-106j24.1 / ANPEP* / P15144* / P97449* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000003680929
ANPEP / si:ch211-276a23.5 / P15144* / P97449* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000008970629
trhde.2 / trhde.1 / thyrotropin releasing hormone degrading enzyme, tandem duplicate 2 / TRHDE* / Q8K093* / Q9UKU6* / thyrotropin releasing hormone degrading enzyme* / Thyrotropin-releasing...ENSDARG0000011183728
trhde.2 / trhde.1 / thyrotropin releasing hormone degrading enzyme, tandem duplicate 1 / TRHDE* / Q8K093* / Q9UKU6* / thyrotropin releasing hormone degrading enzyme* / Thyrotropin-releasing...ENSDARG0000010935828
anpepa / alanyl (membrane) aminopeptidase aENSDARG0000004108325


Protein motifs (from Interpro)
Interpro ID Name
 IPR001930  Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
 IPR014782  Peptidase M1, membrane alanine aminopeptidase, N-terminal
 IPR024571  ERAP1-like C-terminal domain
 IPR034016  Aminopeptidase N-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0043171 peptide catabolic process IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004177 aminopeptidase activity IDA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042277 peptide binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070006 metalloaminopeptidase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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