ENSDARG00000098618


Danio rerio

Features
Gene ID: ENSDARG00000098618
  
Biological name :erap2
  
Synonyms : endoplasmic reticulum aminopeptidase 2 / erap2
  
Possible biological names infered from orthology : Q6P179
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 52226807
Gene end: 52243424
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000136067
NCBI entrez gene - 100144556     See in Manteia.
RefSeq - NM_001123052
RefSeq - XM_005165468
RefSeq Peptide - NP_001116524
swissprot - A0A0R4INQ5
ZFIN ID - ZDB-GENE-080402-6
Ensembl - ENSDARG00000098618
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ERAP2ENSG00000164308Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
erap1b / endoplasmic reticulum aminopeptidase 1b / ERAP1* / Q9EQH2* / Q9NZ08* / endoplasmic reticulum aminopeptidase 1*ENSDARG0000002185951
erap1a / endoplasmic reticulum aminopeptidase 1a / ERAP1* / Q9EQH2* / Q9NZ08* / endoplasmic reticulum aminopeptidase 1*ENSDARG0000001302449
lnpep / leucyl/cystinyl aminopeptidase / Q9UIQ6* / leucyl and cystinyl aminopeptidase*ENSDARG0000010039443
anpepb / alanyl (membrane) aminopeptidase b / ANPEP* / P97449* / P15144* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000010387832
enpep / glutamyl aminopeptidase / P16406* / Q07075*ENSDARG0000005706431
si:ch211-106j24.1 / ANPEP* / P15144* / P97449* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000003680930
ANPEP / si:ch211-276a23.5 / P15144* / P97449* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000008970630
trhde.2 / trhde.1 / thyrotropin releasing hormone degrading enzyme, tandem duplicate 1 / TRHDE* / Q8K093* / Q9UKU6* / thyrotropin releasing hormone degrading enzyme* / Thyrotropin-releasing...ENSDARG0000010935830
si:ch211-147g22.5 / ANPEP* / P15144* / P97449* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000009728530
npepps / aminopeptidase puromycin sensitive / P55786* / Q11011* / Puromycin-sensitive aminopeptidase *ENSDARG0000004494330
trhde.2 / trhde.1 / thyrotropin releasing hormone degrading enzyme, tandem duplicate 2 / TRHDE* / Q8K093* / Q9UKU6* / thyrotropin releasing hormone degrading enzyme* / Thyrotropin-releasing...ENSDARG0000011183730
anpepa / alanyl (membrane) aminopeptidase aENSDARG0000004108329


Protein motifs (from Interpro)
Interpro ID Name
 IPR014782  Peptidase M1, membrane alanine aminopeptidase, N-terminal
 IPR024571  ERAP1-like C-terminal domain
 IPR034016  Aminopeptidase N-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070006 metalloaminopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr