ENSDARG00000109358


Danio rerio

Features
Gene ID: ENSDARG00000109358
  
Biological name :trhde.1
  
Synonyms : thyrotropin releasing hormone degrading enzyme, tandem duplicate 1 / trhde.1 / trhde.2
  
Possible biological names infered from orthology : Q8K093 / Q9UKU6 / Thyrotropin-releasing hormone-degrading ectoenzyme / thyrotropin releasing hormone degrading enzyme / TRHDE
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 23223881
Gene end: 23408029
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000083559
Ensembl peptide - ENSDARP00000117337
swissprot - B0R0S7
swissprot - F1Q5Y3
ZFIN ID - ZDB-GENE-070705-89
ZFIN ID - ZDB-GENE-170406-2
Ensembl - ENSDARG00000109358
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TRHDEENSGALG00000010200Gallus gallus
 TRHDEENSG00000072657Homo sapiens
 TrhdeENSMUSG00000050663Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
trhde.2 / trhde.1 / thyrotropin releasing hormone degrading enzyme, tandem duplicate 2 / TRHDE* / Q8K093* / Q9UKU6* / thyrotropin releasing hormone degrading enzyme* / Thyrotropin-releasing...ENSDARG0000011183799
anpepb / alanyl (membrane) aminopeptidase b / ANPEP* / P97449* / P15144* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000010387832
si:ch211-106j24.1 / ANPEP* / P15144* / P97449* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000003680932
si:ch211-147g22.5 / ANPEP* / P15144* / P97449* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000009728531
ANPEP / si:ch211-276a23.5 / P15144* / P97449* / Aminopeptidase N * / alanyl aminopeptidase, membrane*ENSDARG0000008970630
anpepa / alanyl (membrane) aminopeptidase aENSDARG0000004108329
erap2 / endoplasmic reticulum aminopeptidase 2 / Q6P179*ENSDARG0000009861829
lnpep / leucyl/cystinyl aminopeptidase / Q9UIQ6* / leucyl and cystinyl aminopeptidase*ENSDARG0000010039429
erap1a / endoplasmic reticulum aminopeptidase 1a / ERAP1* / Q9EQH2* / Q9NZ08* / endoplasmic reticulum aminopeptidase 1*ENSDARG0000001302428
erap1b / endoplasmic reticulum aminopeptidase 1b / ERAP1* / Q9EQH2* / Q9NZ08* / endoplasmic reticulum aminopeptidase 1*ENSDARG0000002185928
enpep / glutamyl aminopeptidase / P16406* / Q07075*ENSDARG0000005706427
npepps / aminopeptidase puromycin sensitive / P55786* / Q11011* / Puromycin-sensitive aminopeptidase *ENSDARG0000004494326


Protein motifs (from Interpro)
Interpro ID Name
 IPR001930  Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
 IPR014782  Peptidase M1, membrane alanine aminopeptidase, N-terminal
 IPR015570  Pyroglutamyl-peptidase II
 IPR024571  ERAP1-like C-terminal domain
 IPR034016  Aminopeptidase N-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0008217 regulation of blood pressure IBA
 biological_processGO:0043171 peptide catabolic process IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042277 peptide binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070006 metalloaminopeptidase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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