ENSMUSG00000050663


Mus musculus

Features
Gene ID: ENSMUSG00000050663
  
Biological name :Trhde
  
Synonyms : Q8K093 / Thyrotropin-releasing hormone-degrading ectoenzyme / Trhde
  
Possible biological names infered from orthology : Q9UKU6 / thyrotropin releasing hormone degrading enzyme
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D2
Gene start: 114398823
Gene end: 114802307
  
Corresponding Affymetrix probe sets: 10372421 (MoGene1.0st)   1457156_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000057449
NCBI entrez gene - 237553     See in Manteia.
MGI - MGI:2384311
RefSeq - NM_146241
RefSeq Peptide - NP_666353
swissprot - Q8K093
Ensembl - ENSMUSG00000050663
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trhde.1ENSDARG00000111837Danio rerio
 trhde.1ENSDARG00000109358Danio rerio
 TRHDEENSGALG00000010200Gallus gallus
 TRHDEENSG00000072657Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Anpep / P97449 / Aminopeptidase N / P15144* / alanyl aminopeptidase, membrane*ENSMUSG0000003906230
Enpep / P16406 / glutamyl aminopeptidase / Q07075*ENSMUSG0000002802429
Erap1 / Q9EQH2 / Endoplasmic reticulum aminopeptidase 1 / Q9NZ08*ENSMUSG0000002158329
Lnpep / Q8C129 / Leucyl-cystinyl aminopeptidase / Q9UIQ6* / leucyl and cystinyl aminopeptidase*ENSMUSG0000002384528
Lvrn / laeverin / Q6Q4G3*ENSMUSG0000002448127
Npepps / Q11011 / Puromycin-sensitive aminopeptidase / P55786* / aminopeptidase puromycin sensitive*ENSMUSG0000000144126


Protein motifs (from Interpro)
Interpro ID Name
 IPR001930  Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
 IPR014782  Peptidase M1, membrane alanine aminopeptidase, N-terminal
 IPR015570  Pyroglutamyl-peptidase II
 IPR024571  ERAP1-like C-terminal domain
 IPR034016  Aminopeptidase N-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0008217 regulation of blood pressure IBA
 biological_processGO:0043171 peptide catabolic process IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042277 peptide binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070006 metalloaminopeptidase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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