ENSGALG00000000545


Gallus gallus

Features
Gene ID: ENSGALG00000000545
  
Biological name :REN
  
Synonyms : REN / renin
  
Possible biological names infered from orthology : Mus musculus renin 2 tandem duplication of Ren1 (Ren2), mRNA. / P00797 / P06281 / Ren1
  
Species: Gallus gallus
  
Chr. number: 26
Strand: -1
Band:
Gene start: 1715950
Gene end: 1719075
  
Corresponding Affymetrix probe sets: GgaAffx.341.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000000756
NCBI entrez gene - 431167     See in Manteia.
RefSeq - XM_004934900
RefSeq - XM_015299120
RefSeq - XM_015299118
RefSeq - XM_015299119
swissprot - F1NLA4
Ensembl - ENSGALG00000000545
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 renENSDARG00000041858Danio rerio
 RENENSG00000143839Homo sapiens
 Ren1ENSMUSG00000070645Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CTSD / Q05744 / Cathepsin D Cathepsin D light chain Cathepsin D heavy chain / P07339* / P18242* / AC068580.4* / AC034099.1* / cathepsin D*ENSGALG0000000661346
CTSE / cathepsin E / P14091* / P70269*ENSGALG0000000078641
PGA3 / embryonic pepsinogen precursor / Cym* / chymosin*ENSGALG0000000043738
CTSEAL / Gallus gallus cathepsin E-A-like (CTSEAL), mRNA.ENSGALG0000001001838
PGA5 / pepsin A precursor / PGA4* / PGA3* / P0DJD8* / P0DJD9* / P0DJD7* / pepsinogen 4, group I (pepsinogen A)* / pepsinogen 3, group I (pepsinogen A)* / pepsinogen 5, group I (pepsinogen A)*ENSGALG0000003924236
PGC / progastricsin / P20142* / Q9D7R7* / Gastricsin *ENSGALG0000002848935
PGCENSGALG0000000343535


Protein motifs (from Interpro)
Interpro ID Name
 IPR001461  Aspartic peptidase A1 family
 IPR001969  Aspartic peptidase, active site
 IPR012848  Aspartic peptidase, N-terminal
 IPR021109  Aspartic peptidase domain superfamily
 IPR033121  Peptidase family A1 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0001823 mesonephros development IEA
 biological_processGO:0002003 angiotensin maturation IEA
 biological_processGO:0002016 regulation of blood volume by renin-angiotensin IEA
 biological_processGO:0002018 renin-angiotensin regulation of aldosterone production IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0009755 hormone-mediated signaling pathway IEA
 biological_processGO:0010033 response to organic substance IEA
 biological_processGO:0042756 drinking behavior IEA
 biological_processGO:0043408 regulation of MAPK cascade IEA
 biological_processGO:0048469 cell maturation IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0045177 apical part of cell IEA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IBA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of Angiotensinogen to Angiotensins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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