ENSGALG00000006613


Gallus gallus

Features
Gene ID: ENSGALG00000006613
  
Biological name :CTSD
  
Synonyms : Cathepsin D Cathepsin D light chain Cathepsin D heavy chain / CTSD / Q05744
  
Possible biological names infered from orthology : AC034099.1 / AC068580.4 / cathepsin D / P07339 / P18242
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 14123783
Gene end: 14134951
  
Corresponding Affymetrix probe sets: Gga.1094.1.S1_at (Chicken Array)   Gga.1094.1.S2_at (Chicken Array)   GgaAffx.21992.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010662
NCBI entrez gene - 396090     See in Manteia.
RefSeq - NM_205177
RefSeq Peptide - NP_990508
swissprot - Q05744
Ensembl - ENSGALG00000006613
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctsdENSDARG00000057698Danio rerio
 AC068580.4ENSG00000250644Homo sapiens
 CTSDENSG00000117984Homo sapiens
 AC034099.1ENSMUSG00000110040Mus musculus
 CtsdENSMUSG00000007891Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CTSE / cathepsin E / P14091* / P70269*ENSGALG0000000078646
CTSEAL / Gallus gallus cathepsin E-A-like (CTSEAL), mRNA.ENSGALG0000001001845
REN / renin / Ren1* / P06281* / P00797* / Mus musculus renin 2 tandem duplication of Ren1 (Ren2), mRNA.*ENSGALG0000000054544
PGA5 / pepsin A precursor / PGA4* / PGA3* / P0DJD8* / P0DJD9* / P0DJD7* / pepsinogen 4, group I (pepsinogen A)* / pepsinogen 3, group I (pepsinogen A)* / pepsinogen 5, group I (pepsinogen A)*ENSGALG0000003924241
PGCENSGALG0000000343540
PGA3 / embryonic pepsinogen precursor / Cym* / chymosin*ENSGALG0000000043739
PGC / progastricsin / P20142* / Q9D7R7* / Gastricsin *ENSGALG0000002848935


Protein motifs (from Interpro)
Interpro ID Name
 IPR001461  Aspartic peptidase A1 family
 IPR001969  Aspartic peptidase, active site
 IPR021109  Aspartic peptidase domain superfamily
 IPR033121  Peptidase family A1 domain
 IPR033144  Cathepsin D


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0006914 autophagy IBA
 biological_processGO:0008219 cell death IEP
 biological_processGO:0012501 programmed cell death IDA
 biological_processGO:0030163 protein catabolic process IBA
 cellular_componentGO:0005764 lysosome IDA
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Metabolism of Angiotensinogen to Angiotensins
MHC class II antigen presentation
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006613 CTSD / Q05744 / Cathepsin D Cathepsin D light chain Cathepsin D heavy chain / P07339* / P18242* / AC068580.4* / AC034099.1* / cathepsin D*  / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr