ENSGALG00000000892


Gallus gallus

Features
Gene ID: ENSGALG00000000892
  
Biological name :IL10
  
Synonyms : IL10 / Interleukin-10 / Q6A2H4
  
Possible biological names infered from orthology : P18893 / P22301
  
Species: Gallus gallus
  
Chr. number: 26
Strand: -1
Band:
Gene start: 2562267
Gene end: 2564556
  
Corresponding Affymetrix probe sets: GgaAffx.581.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001310
NCBI entrez gene - 428264     See in Manteia.
RefSeq - NM_001004414
RefSeq Peptide - NP_001004414
swissprot - B6RCP7
swissprot - Q6A2H4
Ensembl - ENSGALG00000000892
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il10ENSDARG00000078147Danio rerio
 IL10ENSG00000136634Homo sapiens
 Il10ENSMUSG00000016529Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000098  Interleukin-10
 IPR009079  Four-helical cytokine-like, core
 IPR020443  Interleukin-10/19/20/22/24/26 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IEA
 biological_processGO:0002237 response to molecule of bacterial origin IEA
 biological_processGO:0002740 negative regulation of cytokine secretion involved in immune response IEA
 biological_processGO:0002826 negative regulation of T-helper 1 type immune response IC
 biological_processGO:0002875 negative regulation of chronic inflammatory response to antigenic stimulus IEA
 biological_processGO:0002904 positive regulation of B cell apoptotic process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0030886 negative regulation of myeloid dendritic cell activation IEA
 biological_processGO:0030889 negative regulation of B cell proliferation IEA
 biological_processGO:0032689 negative regulation of interferon-gamma production IEA
 biological_processGO:0032695 negative regulation of interleukin-12 production IEA
 biological_processGO:0032715 negative regulation of interleukin-6 production IEA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IEA
 biological_processGO:0032800 receptor biosynthetic process IEA
 biological_processGO:0034115 negative regulation of heterotypic cell-cell adhesion IEA
 biological_processGO:0035729 cellular response to hepatocyte growth factor stimulus IEA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0042832 defense response to protozoan NAS
 biological_processGO:0044130 negative regulation of growth of symbiont in host IEA
 biological_processGO:0045019 negative regulation of nitric oxide biosynthetic process IDA
 biological_processGO:0045077 negative regulation of interferon-gamma biosynthetic process IDA
 biological_processGO:0045348 positive regulation of MHC class II biosynthetic process IEA
 biological_processGO:0045787 positive regulation of cell cycle IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0050715 positive regulation of cytokine secretion IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0051045 negative regulation of membrane protein ectodomain proteolysis IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0051384 response to glucocorticoid IEA
 biological_processGO:0060302 negative regulation of cytokine activity IEA
 biological_processGO:0060670 branching involved in labyrinthine layer morphogenesis IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:1903034 regulation of response to wounding IEA
 biological_processGO:1903208 negative regulation of hydrogen peroxide-induced neuron death IEA
 biological_processGO:1903672 positive regulation of sprouting angiogenesis IEA
 biological_processGO:1904706 negative regulation of vascular smooth muscle cell proliferation IEA
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IEA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-10 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000011031 JAK1 / tyrosine-protein kinase JAK1 / P23458* / Janus kinase 1*  / complex / reaction
 ENSGALG00000000892 IL10 / Q6A2H4 / Interleukin-10 / P18893* / P22301*  / complex / reaction
 ENSGALG00000003267 STAT3 / Q6DV79 / Signal transducer and activator of transcription 3 / P40763* / P42227*  / reaction / complex






 

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