ENSGALG00000001708


Gallus gallus

Features
Gene ID: ENSGALG00000001708
  
Biological name :MED1
  
Synonyms : MED1 / mediator complex subunit 1
  
Possible biological names infered from orthology : Mediator of RNA polymerase II transcription subunit 1 / Q15648 / Q925J9
  
Species: Gallus gallus
  
Chr. number: 27
Strand: -1
Band:
Gene start: 4561652
Gene end: 4572376
  
Corresponding Affymetrix probe sets: GgaAffx.24919.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000002620
NCBI entrez gene - 420004     See in Manteia.
RefSeq - XM_418125
swissprot - E1BUI5
Ensembl - ENSGALG00000001708
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 med1ENSDARG00000075340Danio rerio
 MED1ENSG00000125686Homo sapiens
 Med1ENSMUSG00000018160Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000003711215


Protein motifs (from Interpro)
Interpro ID Name
 IPR019680  Mediator complex, subunit Med1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000902 cell morphogenesis IEA
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0001892 embryonic placenta development IEA
 biological_processGO:0002088 lens development in camera-type eye IEA
 biological_processGO:0002154 thyroid hormone mediated signaling pathway IEA
 biological_processGO:0003222 ventricular trabecula myocardium morphogenesis IEA
 biological_processGO:0003406 retinal pigment epithelium development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006356 regulation of transcription by RNA polymerase I IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter IEA
 biological_processGO:0006590 thyroid hormone generation IEA
 biological_processGO:0006702 androgen biosynthetic process IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0007595 lactation IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0009887 animal organ morphogenesis IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010839 negative regulation of keratinocyte proliferation IEA
 biological_processGO:0030216 keratinocyte differentiation IEA
 biological_processGO:0030224 monocyte differentiation IEA
 biological_processGO:0030518 intracellular steroid hormone receptor signaling pathway IEA
 biological_processGO:0030521 androgen receptor signaling pathway IEA
 biological_processGO:0031100 animal organ regeneration IEA
 biological_processGO:0033148 positive regulation of intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0033160 positive regulation of protein import into nucleus, translocation IEA
 biological_processGO:0033598 mammary gland epithelial cell proliferation IEA
 biological_processGO:0033601 positive regulation of mammary gland epithelial cell proliferation IEA
 biological_processGO:0035050 embryonic heart tube development IEA
 biological_processGO:0035116 embryonic hindlimb morphogenesis IEA
 biological_processGO:0035162 embryonic hemopoiesis IEA
 biological_processGO:0035357 peroxisome proliferator activated receptor signaling pathway IEA
 biological_processGO:0035729 cellular response to hepatocyte growth factor stimulus IEA
 biological_processGO:0035855 megakaryocyte development IEA
 biological_processGO:0042789 mRNA transcription by RNA polymerase II IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0045618 positive regulation of keratinocyte differentiation IEA
 biological_processGO:0045648 positive regulation of erythrocyte differentiation IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048821 erythrocyte development IEA
 biological_processGO:0048822 enucleate erythrocyte development IEA
 biological_processGO:0060335 positive regulation of interferon-gamma-mediated signaling pathway IEA
 biological_processGO:0060744 mammary gland branching involved in thelarche IEA
 biological_processGO:0060745 mammary gland branching involved in pregnancy IEA
 biological_processGO:0060750 epithelial cell proliferation involved in mammary gland duct elongation IEA
 biological_processGO:0070318 positive regulation of G0 to G1 transition IEA
 biological_processGO:0070371 ERK1 and ERK2 cascade IEA
 biological_processGO:0070562 regulation of vitamin D receptor signaling pathway IEA
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus IEA
 biological_processGO:0071383 cellular response to steroid hormone stimulus IEA
 biological_processGO:0097067 cellular response to thyroid hormone stimulus IEA
 biological_processGO:2000273 positive regulation of signaling receptor activity IEA
 biological_processGO:2000347 positive regulation of hepatocyte proliferation IEA
 biological_processGO:2001141 regulation of RNA biosynthetic process IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0016592 mediator complex IBA
 molecular_functionGO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0001047 core promoter binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003712 transcription coregulator activity IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0016922 nuclear receptor binding IEA
 molecular_functionGO:0030331 estrogen receptor binding IEA
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IEA
 molecular_functionGO:0030375 thyroid hormone receptor coactivator activity IEA
 molecular_functionGO:0035257 nuclear hormone receptor binding IEA
 molecular_functionGO:0036033 mediator complex binding IEA
 molecular_functionGO:0042809 vitamin D receptor binding IEA
 molecular_functionGO:0042974 retinoic acid receptor binding IEA
 molecular_functionGO:0042975 peroxisome proliferator activated receptor binding IEA
 molecular_functionGO:0046966 thyroid hormone receptor binding IEA
 molecular_functionGO:0050693 LBD domain binding IEA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway
Nuclear Receptor transcription pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr