ENSGALG00000002470


Gallus gallus

Features
Gene ID: ENSGALG00000002470
  
Biological name :CYP27A1
  
Synonyms : CYP27A1 / cytochrome P450 family 27 subfamily A member 1
  
Possible biological names infered from orthology : Q02318 / Q9DBG1 / Sterol 26-hydroxylase, mitochondrial
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 22543083
Gene end: 22545995
  
Corresponding Affymetrix probe sets: Gga.15138.1.A1_at (Chicken Array)   Gga.6135.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003890
Ensembl peptide - ENSGALP00000060846
NCBI entrez gene - 431683     See in Manteia.
RefSeq - XM_422056
swissprot - A0A1L1RPX1
swissprot - F1NVU2
Ensembl - ENSGALG00000002470
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp27a1.2ENSDARG00000069186Danio rerio
 cyp27a1.4ENSDARG00000055159Danio rerio
 cyp27a7ENSDARG00000033802Danio rerio
 zgc:136333ENSDARG00000088013Danio rerio
 Q02318ENSG00000135929Homo sapiens
 Q9DBG1ENSMUSG00000026170Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q4G0S4* / CYP27C1* / cytochrome P450 family 27 subfamily C member 1*ENSGALG0000001153239
CYP24A1 / 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial / Q07973* / Q64441* / cytochrome P450 family 24 subfamily A member 1*ENSGALG0000004227933
CYP11A1 / cholesterol side-chain cleavage enzyme, mitochondrial / P05108* / Q9QZ82* / cytochrome P450 family 11 subfamily A member 1*ENSGALG0000003498232
TBXAS1 / thromboxane A synthase 1 / P24557* / P36423* / thromboxane A synthase 1, platelet*ENSGALG0000001279122
CYP46A1 / cytochrome P450 family 46 subfamily A member 1 / Q9WVK8* / Q9Y6A2* / Cholesterol 24-hydroxylase *ENSGALG0000001116221
CYP3A5 / cytochrome P450 family 3 subfamily A member 5 / P20815* / P08684* / O09158* / Q9JMA7* / Q9HB55* / CYP3A4* / CYP3A7* / Q64464* / Q64481* / Q64459* / P24462* / Cyp3a11* / Cyp3a13* /...ENSGALG0000000444920
CYP3A4 / Gallus gallus cytochrome P450 family 3 subfamily A member 4 (CYP3A4), mRNA.ENSGALG0000000443620


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Synthesis of bile acids and bile salts via 27-hydroxycholesterol
Endogenous sterols


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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