ENSGALG00000002562


Gallus gallus

Features
Gene ID: ENSGALG00000002562
  
Biological name :ARAP3
  
Synonyms : ARAP3 / ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
  
Possible biological names infered from orthology : Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 / Q8R5G7 / Q8WWN8
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 1939272
Gene end: 1953501
  
Corresponding Affymetrix probe sets: Gga.13136.2.A1_at (Chicken Array)   Gga.13136.2.S1_a_at (Chicken Array)   GgaAffx.1685.1.S1_at (Chicken Array)   GgaAffx.1701.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004038
Ensembl peptide - ENSGALP00000051182
NCBI entrez gene - 416196     See in Manteia.
RefSeq - XM_015293632
RefSeq - XM_015293630
RefSeq - XM_015293631
RefSeq - XM_015293628
RefSeq - XM_015293629
swissprot - E1C2Q5
swissprot - A0A1D5PEH9
Ensembl - ENSGALG00000002562
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arap3ENSDARG00000076801Danio rerio
 ARAP3ENSG00000120318Homo sapiens
 Arap3ENSMUSG00000024451Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARAP2 / ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 / Q8WZ64*ENSGALG0000004137332
ARHGAP5 / Rho GTPase activating protein 5 / Q13017*ENSGALG0000000999210


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR000198  Rho GTPase-activating protein domain
 IPR001164  Arf GTPase activating protein
 IPR001660  Sterile alpha motif domain
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0035021 negative regulation of Rac protein signal transduction IEA
 biological_processGO:0035024 negative regulation of Rho protein signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030027 lamellipodium IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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