ENSGALG00000002943


Gallus gallus

Features
Gene ID: ENSGALG00000002943
  
Biological name :PRPF8
  
Synonyms : pre-mRNA processing factor 8 / PRPF8
  
Possible biological names infered from orthology : Pre-mRNA-processing-splicing factor 8 / Q6P2Q9 / Q99PV0
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 5344523
Gene end: 5362178
  
Corresponding Affymetrix probe sets: Gga.1012.1.S1_at (Chicken Array)   GgaAffx.1877.1.S1_s_at (Chicken Array)   GgaAffx.25694.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004641
NCBI entrez gene - 417559     See in Manteia.
RefSeq - XM_415805
swissprot - E1BZT5
Ensembl - ENSGALG00000002943
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prpf8ENSDARG00000026180Danio rerio
 PRPF8ENSG00000174231Homo sapiens
 Prpf8ENSMUSG00000020850Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000555  JAB1/MPN/MOV34 metalloenzyme domain
 IPR012337  Ribonuclease H-like superfamily
 IPR012591  PRO8NT domain
 IPR012592  PROCN domain
 IPR012984  PROCT domain
 IPR019580  Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding
 IPR019581  Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding
 IPR019582  RNA recognition motif, spliceosomal PrP8
 IPR021983  PRP8 domain IV core
 IPR027652  Pre-mRNA-processing-splicing factor 8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000244 spliceosomal tri-snRNP complex assembly IEA
 biological_processGO:0000398 mRNA splicing, via spliceosome IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005682 U5 snRNP IBA
 cellular_componentGO:0046540 U4/U6 x U5 tri-snRNP complex IEA
 cellular_componentGO:0071007 U2-type catalytic step 2 spliceosome IEA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IEA
 molecular_functionGO:0000386 second spliceosomal transesterification activity IBA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0017070 U6 snRNA binding IBA
 molecular_functionGO:0030619 U1 snRNA binding IBA
 molecular_functionGO:0030620 U2 snRNA binding IBA
 molecular_functionGO:0030623 U5 snRNA binding IBA
 molecular_functionGO:0070530 K63-linked polyubiquitin modification-dependent protein binding IEA
 molecular_functionGO:0097157 pre-mRNA intronic binding IBA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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