ENSDARG00000026180


Danio rerio

Features
Gene ID: ENSDARG00000026180
  
Biological name :prpf8
  
Synonyms : pre-mRNA processing factor 8 / prpf8
  
Possible biological names infered from orthology : Pre-mRNA-processing-splicing factor 8 / Q6P2Q9 / Q99PV0
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 28248052
Gene end: 28262709
  
Corresponding Affymetrix probe sets: Dr.25624.3.S1_at (Zebrafish Array)   Dr.5452.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000121091
Ensembl peptide - ENSDARP00000143855
NCBI entrez gene - 393951     See in Manteia.
RefSeq - NM_200976
RefSeq - XM_005157646
RefSeq Peptide - NP_957270
swissprot - A0A286YA65
swissprot - A0A0R4J8E6
ZFIN ID - ZDB-GENE-030131-577
Ensembl - ENSDARG00000026180
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRPF8ENSGALG00000002943Gallus gallus
 PRPF8ENSG00000174231Homo sapiens
 Prpf8ENSMUSG00000020850Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000555  JAB1/MPN/MOV34 metalloenzyme domain
 IPR012337  Ribonuclease H-like superfamily
 IPR012591  PRO8NT domain
 IPR012592  PROCN domain
 IPR012984  PROCT domain
 IPR019580  Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding
 IPR019581  Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding
 IPR019582  RNA recognition motif, spliceosomal PrP8
 IPR021983  PRP8 domain IV core
 IPR027652  Pre-mRNA-processing-splicing factor 8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000244 spliceosomal tri-snRNP complex assembly IMP
 biological_processGO:0000398 mRNA splicing, via spliceosome IEA
 cellular_componentGO:0005681 spliceosomal complex IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0017070 U6 snRNA binding IEA
 molecular_functionGO:0030623 U5 snRNA binding IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain degenerate , abnormal
Show

 ZFA:0000012 central nervous system central nervous system apoptotic , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000075 spinal cord spinal cord degenerate , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001117 post-vent region post-vent region kinked , abnormal
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 ZFA:0009326 myeloid leukocyte myeloid leukocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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