ENSGALG00000003977


Gallus gallus

Features
Gene ID: ENSGALG00000003977
  
Biological name :TWF2
  
Synonyms : TWF2 / twinfilin-2
  
Possible biological names infered from orthology : Q6IBS0 / Q9Z0P5 / twinfilin actin binding protein 2
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 2935766
Gene end: 2954190
  
Corresponding Affymetrix probe sets: GgaAffx.11652.1.S1_at (Chicken Array)   GgaAffx.11652.1.S1_s_at (Chicken Array)   GgaAffx.26075.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052343
Ensembl peptide - ENSGALP00000006326
NCBI entrez gene - 415940     See in Manteia.
RefSeq - XM_015292837
RefSeq - XM_015292834
RefSeq - XM_015292835
RefSeq - XM_015292836
RefSeq - NM_001030589
RefSeq - XM_015292829
RefSeq - XM_015292830
RefSeq - XM_015292831
RefSeq - XM_015292833
RefSeq Peptide - NP_001025760
swissprot - F1NZP0
swissprot - A0A1D5PHR3
Ensembl - ENSGALG00000003977
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 twf2aENSDARG00000094792Danio rerio
 twf2bENSDARG00000009727Danio rerio
 TWF2ENSG00000247596Homo sapiens
 Twf2ENSMUSG00000023277Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TWF1 / twinfilin-1 isoform 2 / Q12792* / Q91YR1* / twinfilin actin binding protein 1*ENSGALG0000000959566


Protein motifs (from Interpro)
Interpro ID Name
 IPR002108  Actin-depolymerising factor homology domain
 IPR028458  Twinfilin
 IPR029006  ADF-H/Gelsolin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010592 positive regulation of lamellipodium assembly IEA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0030837 negative regulation of actin filament polymerization IEA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IEA
 biological_processGO:0045773 positive regulation of axon extension IEA
 biological_processGO:0071300 cellular response to retinoic acid IEA
 biological_processGO:0071363 cellular response to growth factor stimulus IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0032420 stereocilium IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0003785 actin monomer binding IEA
 molecular_functionGO:0005080 protein kinase C binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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