ENSGALG00000004003


Gallus gallus

Features
Gene ID: ENSGALG00000004003
  
Biological name :AIFM1
  
Synonyms : AIFM1 / apoptosis-inducing factor 1, mitochondrial
  
Possible biological names infered from orthology : apoptosis inducing factor mitochondria associated 1 / O95831 / Q9Z0X1
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 1590795
Gene end: 1602749
  
Corresponding Affymetrix probe sets: Gga.11032.1.A1_at (Chicken Array)   Gga.11032.1.S1_at (Chicken Array)   Gga.17885.1.S1_at (Chicken Array)   GgaAffx.13220.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000006366
Ensembl peptide - ENSGALP00000063248
Ensembl peptide - ENSGALP00000062991
Ensembl peptide - ENSGALP00000057474
NCBI entrez gene - 428688     See in Manteia.
RefSeq - NM_001007490
RefSeq Peptide - NP_001007491
swissprot - A0A1L1RWN0
swissprot - A0A1D6UPT4
swissprot - A0A1D5PWY4
swissprot - Q5F357
Ensembl - ENSGALG00000004003
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aifm1ENSDARG00000058088Danio rerio
 AIFM1ENSG00000156709Homo sapiens
 Aifm1ENSMUSG00000036932Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AIFM3 / apoptosis inducing factor, mitochondria associated 3 / Q3TY86* / Q96NN9* / Apoptosis-inducing factor 3 *ENSGALG0000000772017
ENSGALG0000002378715


Protein motifs (from Interpro)
Interpro ID Name
 IPR004099  Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
 IPR016156  FAD/NAD-linked reductase, dimerisation domain superfamily
 IPR023753  FAD/NAD(P)-binding domain
 IPR029324  Mitochondrial apoptosis-inducing factor, C-terminal domain
 IPR032773  Protein MGARP, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0010942 positive regulation of cell death IEA
 biological_processGO:0051402 neuron apoptotic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA
 biological_processGO:1902510 regulation of apoptotic DNA fragmentation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005758 mitochondrial intermembrane space IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0016174 NAD(P)H oxidase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016651 oxidoreductase activity, acting on NAD(P)H IEA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0071949 FAD binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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