ENSGALG00000004333


Gallus gallus

Features
Gene ID: ENSGALG00000004333
  
Biological name :ABCA5
  
Synonyms : ABCA5 / ATP binding cassette subfamily A member 5
  
Possible biological names infered from orthology : ATP-binding cassette, sub-family A (ABC1), member 5 / Q8K448 / Q8WWZ7
  
Species: Gallus gallus
  
Chr. number: 18
Strand: -1
Band:
Gene start: 8021312
Gene end: 8048227
  
Corresponding Affymetrix probe sets: Gga.10223.1.S1_s_at (Chicken Array)   Gga.2515.1.S1_at (Chicken Array)   GgaAffx.26175.1.S1_at (Chicken Array)   GgaAffx.2699.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000006896
Ensembl peptide - ENSGALP00000052461
NCBI entrez gene - 417444     See in Manteia.
RefSeq - XM_015279942
RefSeq - XM_015279943
RefSeq - XM_415695
swissprot - E1BY40
swissprot - A0A1D5PI29
Ensembl - ENSGALG00000004333
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abca5ENSDARG00000074041Danio rerio
 ABCA5ENSG00000154265Homo sapiens
 Abca5ENSMUSG00000018800Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ABCA8* / ABCA9* / ABCA6* / ABCA10* / Abca8a* / Abca8b* / O94911* / Q8IUA7* / Q8K440* / Q8K441* / Q8K442* / Q8K449* / Q8N139* / Q8WWZ4* / ATP binding cassette subfamily A member 6* / ATP bin...ENSGALG0000002139942
ABCA8* / ABCA9* / ABCA6* / ABCA10* / Abca8a* / Abca8b* / O94911* / Q8IUA7* / Q8K440* / Q8K441* / Q8K442* / Q8K449* / Q8N139* / Q8WWZ4* / ATP binding cassette subfamily A member 6* / ATP bin...ENSGALG0000002139536
ABCA7 / ATP binding cassette subfamily A member 7 / Q8IZY2* / Q91V24* / ATP-binding cassette, sub-family A (ABC1), member 7*ENSGALG0000000245326
ABCA1 / ATP-binding cassette sub-family A member 1 / O95477* / P41233* / ATP binding cassette subfamily A member 1* / ATP-binding cassette, sub-family A (ABC1), member 1*ENSGALG0000001543326
ABCA4 / ATP binding cassette subfamily A member 4 / O35600* / P78363* / ATP-binding cassette, sub-family A (ABC1), member 4*ENSGALG0000000575226
ABCA3 / ATP binding cassette subfamily A member 3 / Abca17* / Abca14* / Abca15* / Abca16* / E9PX95* / Q8R420* / Q99758* / ATP-binding cassette, sub-family A (ABC1), member 3* / ATP-binding ...ENSGALG0000003783725
ABCA2 / ATP binding cassette subfamily A member 2 / Q9BZC7* / ATP-binding cassette, sub-family A (ABC1), member 2*ENSGALG0000003689424
ABCA12 / ATP binding cassette subfamily A member 12 / Q86UK0* / ATP-binding cassette, sub-family A (ABC1), member 12*ENSGALG0000000355324
ABCA13* / Q5SSE9* / Q86UQ4* / ATP binding cassette subfamily A member 13* / ATP-binding cassette, sub-family A (ABC1), member 13*ENSGALG0000001307911


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR017871  ABC transporter, conserved site
 IPR026082  ABC transporter A
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030367  ATP-binding cassette subfamily A member 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IBA
 biological_processGO:0010745 negative regulation of macrophage derived foam cell differentiation IEA
 biological_processGO:0030301 cholesterol transport IEA
 biological_processGO:0033344 cholesterol efflux IEA
 biological_processGO:0034375 high-density lipoprotein particle remodeling IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IBA


Pathways (from Reactome)
Pathway description
ABC transporters in lipid homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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