ENSGALG00000004355


Gallus gallus

Features
Gene ID: ENSGALG00000004355
  
Biological name :MCU
  
Synonyms : MCU / mitochondrial calcium uniporter
  
Possible biological names infered from orthology : Calcium uniporter protein, mitochondrial / Q3UMR5 / Q8NE86
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 11260831
Gene end: 11349950
  
Corresponding Affymetrix probe sets: GgaAffx.2714.1.S1_at (Chicken Array)   GgaAffx.2714.2.S1_at (Chicken Array)   GgaAffx.2714.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000006935
Ensembl peptide - ENSGALP00000049377
NCBI entrez gene - 428942     See in Manteia.
RefSeq - XM_015288227
RefSeq - XM_015288228
RefSeq - XM_426497
swissprot - E1BWX3
swissprot - A0A1D5P9H3
Ensembl - ENSGALG00000004355
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mcuENSDARG00000101175Danio rerio
 MCUENSG00000156026Homo sapiens
 McuENSMUSG00000009647Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MCUB / mitochondrial calcium uniporter dominant negative beta subunit / Q810S1* / Q9NWR8* / Calcium uniporter regulatory subunit MCUb, mitochondrial *ENSGALG0000001219649


Protein motifs (from Interpro)
Interpro ID Name
 IPR006769  Coiled-coil domain containing protein 109, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006851 mitochondrial calcium ion transmembrane transport IEA
 biological_processGO:0019722 calcium-mediated signaling IEA
 biological_processGO:0032024 positive regulation of insulin secretion IEA
 biological_processGO:0036444 calcium import into the mitochondrion IBA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0051560 mitochondrial calcium ion homeostasis IBA
 biological_processGO:0051561 positive regulation of mitochondrial calcium ion concentration IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031305 integral component of mitochondrial inner membrane IBA
 cellular_componentGO:0034704 calcium channel complex IEA
 cellular_componentGO:1990246 uniplex complex IBA
 molecular_functionGO:0005262 calcium channel activity IBA
 molecular_functionGO:0015292 uniporter activity IBA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Mitochondrial calcium ion transport
Processing of SMDT1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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