ENSGALG00000004364


Gallus gallus

Features
Gene ID: ENSGALG00000004364
  
Biological name :ABR
  
Synonyms : ABR / active BCR-related
  
Possible biological names infered from orthology : active BCR-related gene / Q12979 / Q5SSL4
  
Species: Gallus gallus
  
Chr. number: 19
Strand: 1
Band:
Gene start: 6317334
Gene end: 6339909
  
Corresponding Affymetrix probe sets: Gga.16745.1.S1_at (Chicken Array)   Gga.16745.2.S1_at (Chicken Array)   Gga.19014.1.S1_at (Chicken Array)   GgaAffx.26186.1.S1_s_at (Chicken Array)   GgaAffx.2719.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000006947
Ensembl peptide - ENSGALP00000050338
Ensembl peptide - ENSGALP00000044836
NCBI entrez gene - 771897     See in Manteia.
RefSeq - XM_004946646
RefSeq - XM_015295831
RefSeq - XM_015295832
RefSeq - XM_015295834
swissprot - A0A1D5PC53
swissprot - A0A1D5NWU3
swissprot - E1BWF8
Ensembl - ENSGALG00000004364
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abrENSDARG00000095180Danio rerio
 ABRENSG00000159842Homo sapiens
 AbrENSMUSG00000017631Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BCR / BCR, RhoGEF and GTPase activating protein / P11274* / Q6PAJ1* / Breakpoint cluster region protein *ENSGALG0000000669568
ARHGAP21 / Rho GTPase activating protein 21 / Q5T5U3*ENSGALG0000000772116
ARHGAP12 / Rho GTPase activating protein 12 / Q8C0D4* / Q8IWW6*ENSGALG0000000725416
Q5ZMM3 / ARHGAP15 / Rho GTPase-activating protein 15 / Q53QZ3* / Q811M1*ENSGALG0000001242114
SYDE2 / synapse defective Rho GTPase homolog 2 / Q5VT97*ENSGALG0000003877613
ARHGAP23 / Rho GTPase activating protein 23 / Q69ZH9* / Q9P227*ENSGALG0000004262812
CHN1 / N-chimaerin / P15882* / Q91V57* / chimerin 1*ENSGALG0000000929311
CHN2* / Q80XD1* / P52757* / AC004593.3* / chimerin 2* / Beta-chimaerin * / beta-chimaerin isoform 3 *ENSGALG0000001116410


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000198  Rho GTPase-activating protein domain
 IPR000219  Dbl homology (DH) domain
 IPR001331  Guanine-nucleotide dissociation stimulator, CDC24, conserved site
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002692 negative regulation of cellular extravasation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0043114 regulation of vascular permeability IEA
 biological_processGO:0043314 negative regulation of neutrophil degranulation IEA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0050766 positive regulation of phagocytosis IEA
 biological_processGO:0050885 neuromuscular process controlling balance IEA
 biological_processGO:0060313 negative regulation of blood vessel remodeling IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IBA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005096 GTPase activator activity IBA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr