ENSGALG00000005547


Gallus gallus

Features
Gene ID: ENSGALG00000005547
  
Biological name :PIK3AP1
  
Synonyms : Phosphoinositide 3-kinase adapter protein 1 / PIK3AP1 / Q9DDT2
  
Possible biological names infered from orthology : phosphoinositide-3-kinase adaptor protein 1 / Q6ZUJ8 / Q9EQ32
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 16723978
Gene end: 16765056
  
Corresponding Affymetrix probe sets: Gga.11560.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000062022
Ensembl peptide - ENSGALP00000008882
Ensembl peptide - ENSGALP00000055674
NCBI entrez gene - 374268     See in Manteia.
RefSeq - XM_015288347
RefSeq - NM_204350
RefSeq - XM_015288344
RefSeq - XM_015288345
RefSeq - XM_015288346
RefSeq Peptide - NP_989681
swissprot - Q9DDT2
swissprot - A0A1D5PRZ5
Ensembl - ENSGALG00000005547
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pik3ap1ENSDARG00000078285Danio rerio
 Q6ZUJ8ENSG00000155629Homo sapiens
 Q9EQ32ENSMUSG00000025017Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BANK1 / B cell scaffold protein with ankyrin repeats 1 / Q80VH0* / Q8NDB2* / B-cell scaffold protein with ankyrin repeats *ENSGALG0000001229223


Protein motifs (from Interpro)
Interpro ID Name
 IPR000157  Toll/interleukin-1 receptor homology (TIR) domain
 IPR017893  DBB domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISS
 biological_processGO:0031929 TOR signaling IMP
 biological_processGO:0032869 cellular response to insulin stimulus IMP
 biological_processGO:0034134 toll-like receptor 2 signaling pathway ISS
 biological_processGO:0034142 toll-like receptor 4 signaling pathway ISS
 biological_processGO:0034154 toll-like receptor 7 signaling pathway ISS
 biological_processGO:0034162 toll-like receptor 9 signaling pathway ISS
 biological_processGO:0042325 regulation of phosphorylation IMP
 biological_processGO:0043549 regulation of kinase activity IMP
 biological_processGO:0050727 regulation of inflammatory response ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding ISS
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
PIP3 activates AKT signaling
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002583 PIK3CD / phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform / O00329* / O35904* / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta*  / complex
 ENSGALG00000014786 PIK3R1 / phosphoinositide-3-kinase regulatory subunit 1 / P26450* / P27986*  / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr