ENSGALG00000005637


Gallus gallus

Features
Gene ID: ENSGALG00000005637
  
Biological name :GBF1
  
Synonyms : GBF1 / golgi brefeldin A resistant guanine nucleotide exchange factor 1
  
Possible biological names infered from orthology : Q92538
  
Species: Gallus gallus
  
Chr. number: 6
Strand: 1
Band:
Gene start: 16830027
Gene end: 16931260
  
Corresponding Affymetrix probe sets: Gga.6986.1.S1_at (Chicken Array)   GgaAffx.26551.1.S1_s_at (Chicken Array)   GgaAffx.26551.2.S1_at (Chicken Array)   GgaAffx.26551.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000009030
NCBI entrez gene - 423758     See in Manteia.
RefSeq - XM_015288459
RefSeq - XM_015288460
RefSeq - XM_015288461
RefSeq - XM_015288462
RefSeq - XM_015288458
swissprot - F1NGJ3
Ensembl - ENSGALG00000005637
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gbf1ENSDARG00000027016Danio rerio
 GBF1ENSG00000107862Homo sapiens
 Gbf1ENSMUSG00000025224Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PSD / pleckstrin and Sec7 domain containing / A5PKW4* / Q5DTT2* / Mus musculus pleckstrin and Sec7 domain containing (Psd), transcript variant 2, mRNA.*ENSGALG000000425519
ENSGALG000000154288
PSD2 / pleckstrin and Sec7 domain containing 2 / Q6P1I6* / Q9BQI7* / PH and SEC7 domain-containing protein 2 *ENSGALG000000308367


Protein motifs (from Interpro)
Interpro ID Name
 IPR000904  Sec7 domain
 IPR016024  Armadillo-type fold
 IPR023394  Sec7, C-terminal domain superfamily
 IPR032691  Guanine nucleotide exchange factor, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002263 cell activation involved in immune response IEA
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IEA
 biological_processGO:0006895 Golgi to endosome transport IEA
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IEA
 biological_processGO:0016192 vesicle-mediated transport IBA
 biological_processGO:0030593 neutrophil chemotaxis IEA
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0034067 protein localization to Golgi apparatus IEA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IEA
 biological_processGO:0048205 COPI coating of Golgi vesicle IEA
 biological_processGO:0061162 establishment of monopolar cell polarity IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0070973 protein localization to endoplasmic reticulum exit site IEA
 biological_processGO:0090166 Golgi disassembly IEA
 biological_processGO:0097111 endoplasmic reticulum-Golgi intermediate compartment organization IEA
 biological_processGO:0098586 cellular response to virus IEA
 biological_processGO:1903409 reactive oxygen species biosynthetic process IEA
 biological_processGO:1903420 protein localization to endoplasmic reticulum tubular network IEA
 biological_processGO:2000008 regulation of protein localization to cell surface IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005801 cis-Golgi network IEA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031252 cell leading edge IEA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IBA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
Clathrin derived vesicle budding
VxPx cargo-targeting to cilium
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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