ENSGALG00000006017


Gallus gallus

Features
Gene ID: ENSGALG00000006017
  
Biological name :DOCK11
  
Synonyms : dedicator of cytokinesis 11 / DOCK11
  
Possible biological names infered from orthology : A2AF47 / Dedicator of cytokinesis protein 11 / Q5JSL3
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 3336057
Gene end: 3405347
  
Corresponding Affymetrix probe sets: Gga.1045.1.S1_at (Chicken Array)   GgaAffx.26702.1.S1_s_at (Chicken Array)   GgaAffx.3741.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049986
Ensembl peptide - ENSGALP00000009669
NCBI entrez gene - 422229     See in Manteia.
RefSeq - XM_015278444
RefSeq - XM_015278442
RefSeq - XM_015278443
RefSeq - XM_015278441
swissprot - F1N9K4
swissprot - A0A1D5PB65
Ensembl - ENSGALG00000006017
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dock11ENSDARG00000062485Danio rerio
 DOCK11ENSG00000147251Homo sapiens
 A2AF47ENSMUSG00000031093Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DOCK9 / dedicator of cytokinesis 9 / Q9BZ29* / dedicator of cytokinesis protein 9 isoform 5 *ENSGALG0000001688360
DOCK10 / dedicator of cytokinesis 10 / Q96BY6*ENSGALG0000000503052
DOCK7* / Q96N67* / dedicator of cytokinesis 7*ENSGALG0000001096718
DOCK8* / Q8C147* / Q8NF50* / dedicator of cytokinesis 8* / Dedicator of cytokinesis protein 8 *ENSGALG0000001015614
DOCK7* / Q96N67* / dedicator of cytokinesis 7*ENSGALG0000004143611
DOCK8* / Q8C147* / Q8NF50* / dedicator of cytokinesis 8* / Dedicator of cytokinesis protein 8 *ENSGALG0000003547310


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR010703  Dedicator of cytokinesis, C-terminal
 IPR011993  PH-like domain superfamily
 IPR016024  Armadillo-type fold
 IPR021816  Dedicator of cytokinesis C/D, N-terminal
 IPR026791  Dedicator of cytokinesis
 IPR027007  DHR-1 domain
 IPR027357  DHR-2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001782 B cell homeostasis IEA
 biological_processGO:0002315 marginal zone B cell differentiation IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051491 positive regulation of filopodium assembly IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007130 RAC1 / Rac family small GTPase 1 / P63000* / P63001* / RAS-related C3 botulinum substrate 1*  / complex / reaction
 ENSGALG00000004796 CDC42 / Q90694 / Cell division control protein 42 homolog / P60766* / P60953* / cell division cycle 42* / Cell division control *  / reaction / complex






 

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