ENSMUSG00000031093


Mus musculus

Features
Gene ID: ENSMUSG00000031093
  
Biological name :Dock11
  
Synonyms : A2AF47 / Dedicator of cytokinesis protein 11 / Dock11
  
Possible biological names infered from orthology : dedicator of cytokinesis 11 / Q5JSL3
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A3.3
Gene start: 35888832
Gene end: 36076562
  
Corresponding Affymetrix probe sets: 10599120 (MoGene1.0st)   1429028_at (Mouse Genome 430 2.0 Array)   1443467_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033419
Ensembl peptide - ENSMUSP00000110921
Ensembl peptide - ENSMUSP00000110919
NCBI entrez gene - 75974     See in Manteia.
MGI - MGI:1923224
RefSeq - XM_006541408
RefSeq - NM_001009947
RefSeq - XM_006541406
RefSeq - XM_006541407
RefSeq Peptide - NP_001009947
swissprot - A2AF47
swissprot - A2AF65
swissprot - A2AF67
Ensembl - ENSMUSG00000031093
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dock11ENSDARG00000062485Danio rerio
 DOCK11ENSGALG00000006017Gallus gallus
 DOCK11ENSG00000147251Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dock9 / dedicator of cytokinesis protein 9 isoform 5 / Q9BZ29* / dedicator of cytokinesis 9*ENSMUSG0000002555860
Dock10 / dedicator of cytokinesis 10 / Q96BY6*ENSMUSG0000003860852
Dock7 / dedicator of cytokinesis 7 / Q96N67*ENSMUSG0000002855630
Dock8 / Q8C147 / Dedicator of cytokinesis protein 8 / Q8NF50* / dedicator of cytokinesis 8*ENSMUSG0000005208529
Dock6 / Q8VDR9 / Dedicator of cytokinesis protein 6 / Q96HP0* / dedicator of cytokinesis 6*ENSMUSG0000003219829


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR010703  Dedicator of cytokinesis, C-terminal
 IPR011989  Armadillo-like helical
 IPR011993  PH-like domain superfamily
 IPR016024  Armadillo-type fold
 IPR021816  Dedicator of cytokinesis C/D, N-terminal
 IPR026791  Dedicator of cytokinesis
 IPR027007  DHR-1 domain
 IPR027357  DHR-2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001782 B cell homeostasis IMP
 biological_processGO:0002315 marginal zone B cell differentiation IMP
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IDA
 biological_processGO:0051491 positive regulation of filopodium assembly IMP
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IDA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0017048 Rho GTPase binding IPI


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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