ENSMUSG00000032198


Mus musculus

Features
Gene ID: ENSMUSG00000032198
  
Biological name :Dock6
  
Synonyms : Dedicator of cytokinesis protein 6 / Dock6 / Q8VDR9
  
Possible biological names infered from orthology : dedicator of cytokinesis 6 / Q96HP0
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A3
Gene start: 21799860
Gene end: 21852635
  
Corresponding Affymetrix probe sets: 10591576 (MoGene1.0st)   10591608 (MoGene1.0st)   10591610 (MoGene1.0st)   10591612 (MoGene1.0st)   10591614 (MoGene1.0st)   10591616 (MoGene1.0st)   10591618 (MoGene1.0st)   10591620 (MoGene1.0st)   10591622 (MoGene1.0st)   10591624 (MoGene1.0st)   10591626 (MoGene1.0st)   10591628 (MoGene1.0st)   10591630 (MoGene1.0st)   10591632 (MoGene1.0st)   10591634 (MoGene1.0st)   1427240_at (Mouse Genome 430 2.0 Array)   1430683_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000149156
Ensembl peptide - ENSMUSP00000150347
Ensembl peptide - ENSMUSP00000150250
Ensembl peptide - ENSMUSP00000034728
NCBI entrez gene - 319899     See in Manteia.
MGI - MGI:1914789
RefSeq - XM_017313427
RefSeq - XM_006510423
RefSeq - XM_011242552
RefSeq - XM_011242553
RefSeq - XM_011242554
RefSeq - XM_011242555
RefSeq - XM_017313426
RefSeq - NM_177030
RefSeq - XM_006510422
RefSeq Peptide - NP_796004
swissprot - E9QPN7
swissprot - A0A1L1STJ1
swissprot - A0A1L1ST98
swissprot - A0A1L1SQR4
swissprot - Q8VDR9
Ensembl - ENSMUSG00000032198
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dock6ENSDARG00000035706Danio rerio
 DOCK6ENSG00000130158Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dock7 / dedicator of cytokinesis 7 / Q96N67*ENSMUSG0000002855666
Dock8 / Q8C147 / Dedicator of cytokinesis protein 8 / Q8NF50* / dedicator of cytokinesis 8*ENSMUSG0000005208552
A2AF47 / Dock11 / Dedicator of cytokinesis protein 11 / Q5JSL3* / dedicator of cytokinesis 11*ENSMUSG0000003109329
Dock9 / dedicator of cytokinesis protein 9 isoform 5 / Q9BZ29* / dedicator of cytokinesis 9*ENSMUSG0000002555828
Dock10 / dedicator of cytokinesis 10 / Q96BY6*ENSMUSG0000003860827


Protein motifs (from Interpro)
Interpro ID Name
 IPR010703  Dedicator of cytokinesis, C-terminal
 IPR021816  Dedicator of cytokinesis C/D, N-terminal
 IPR026791  Dedicator of cytokinesis
 IPR026798  Dedicator of cytokinesis 6
 IPR027007  DHR-1 domain
 IPR027357  DHR-2 domain
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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