ENSGALG00000006037


Gallus gallus

Features
Gene ID: ENSGALG00000006037
  
Biological name :MCM2
  
Synonyms : DNA replication licensing factor MCM2 / MCM2
  
Possible biological names infered from orthology : minichromosome maintenance complex component 2 / P49736 / P97310
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 9749558
Gene end: 9760977
  
Corresponding Affymetrix probe sets: Gga.13180.1.S1_at (Chicken Array)   GgaAffx.11696.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000009709
Ensembl peptide - ENSGALP00000063160
Ensembl peptide - ENSGALP00000059900
NCBI entrez gene - 416027     See in Manteia.
RefSeq - NM_001006139
RefSeq - XM_015293083
RefSeq Peptide - NP_001006139
swissprot - A0A1L1RWE6
swissprot - A0A1L1RMB2
swissprot - F1NB20
Ensembl - ENSGALG00000006037
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mcm2ENSDARG00000102798Danio rerio
 MCM2ENSG00000073111Homo sapiens
 Mcm2ENSMUSG00000002870Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001208  MCM domain
 IPR008045  DNA replication licensing factor Mcm2
 IPR012340  Nucleic acid-binding, OB-fold
 IPR018525  Mini-chromosome maintenance, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027925  MCM N-terminal domain
 IPR031327  Mini-chromosome maintenance protein
 IPR033762  MCM OB domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006268 DNA unwinding involved in DNA replication IEA
 biological_processGO:0006270 DNA replication initiation IEA
 biological_processGO:0006334 nucleosome assembly IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0071353 cellular response to interleukin-4 IEA
 biological_processGO:0090102 cochlea development IEA
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005664 nuclear origin of replication recognition complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0042555 MCM complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003678 DNA helicase activity IEA
 molecular_functionGO:0003688 DNA replication origin binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0042393 histone binding IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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