ENSGALG00000006098


Gallus gallus

Features
Gene ID: ENSGALG00000006098
  
Biological name :HPRT1
  
Synonyms : HPRT1 / Hypoxanthine-guanine phosphoribosyltransferase / Q9W719
  
Possible biological names infered from orthology : Hprt / hypoxanthine phosphoribosyltransferase 1 / P00492 / P00493
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 4053195
Gene end: 4069066
  
Corresponding Affymetrix probe sets: GgaAffx.3804.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051359
Ensembl peptide - ENSGALP00000009829
NCBI entrez gene - 395653     See in Manteia.
RefSeq - NM_204848
RefSeq Peptide - NP_990179
swissprot - Q9W719
swissprot - A0A1D5PEZ7
swissprot - F1NBZ6
Ensembl - ENSGALG00000006098
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hprt1ENSDARG00000008884Danio rerio
 HPRT1ENSG00000165704Homo sapiens
 HprtENSMUSG00000025630Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000000536167
PRTFDC1 / phosphoribosyl transferase domain containing 1 / Q9NRG1*ENSGALG0000000769462


Protein motifs (from Interpro)
Interpro ID Name
 IPR000836  Phosphoribosyltransferase domain
 IPR005904  Hypoxanthine phosphoribosyl transferase
 IPR029057  Phosphoribosyltransferase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001975 response to amphetamine IEA
 biological_processGO:0006164 purine nucleotide biosynthetic process IEA
 biological_processGO:0006166 purine ribonucleoside salvage IEA
 biological_processGO:0006168 adenine salvage IEA
 biological_processGO:0006178 guanine salvage ISS
 biological_processGO:0007625 grooming behavior IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0009116 nucleoside metabolic process IEA
 biological_processGO:0019835 cytolysis IEA
 biological_processGO:0021756 striatum development IEA
 biological_processGO:0021895 cerebral cortex neuron differentiation IEA
 biological_processGO:0021954 central nervous system neuron development IEA
 biological_processGO:0032264 IMP salvage IEA
 biological_processGO:0042417 dopamine metabolic process IEA
 biological_processGO:0043103 hypoxanthine salvage ISS
 biological_processGO:0045964 positive regulation of dopamine metabolic process ISS
 biological_processGO:0046038 GMP catabolic process ISS
 biological_processGO:0046040 IMP metabolic process ISS
 biological_processGO:0046083 adenine metabolic process IEA
 biological_processGO:0046100 hypoxanthine metabolic process ISS
 biological_processGO:0046651 lymphocyte proliferation IEA
 biological_processGO:0048813 dendrite morphogenesis IEA
 biological_processGO:0051289 protein homotetramerization IEA
 cellular_componentGO:0005694 chromosome IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0002057 guanine binding IDA
 molecular_functionGO:0002060 purine nucleobase binding TAS
 molecular_functionGO:0004422 hypoxanthine phosphoribosyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0052657 guanine phosphoribosyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Purine salvage


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006098 HPRT1 / Q9W719 / Hypoxanthine-guanine phosphoribosyltransferase / Hprt* / P00492* / P00493* / hypoxanthine phosphoribosyltransferase 1*  / complex






 

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