ENSGALG00000006799


Gallus gallus

Features
Gene ID: ENSGALG00000006799
  
Biological name :AP2A2
  
Synonyms : AP2A2 / AP-2 complex subunit alpha-2
  
Possible biological names infered from orthology : adaptor related protein complex 2 alpha 2 subunit / Mus musculus adaptor-related protein complex 2, alpha 2 subunit (Ap2a2), transcript variant 1, mRNA. / O94973 / P17427
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 15100354
Gene end: 15143253
  
Corresponding Affymetrix probe sets: Gga.1263.1.S1_at (Chicken Array)   Gga.13041.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010984
Ensembl peptide - ENSGALP00000044267
NCBI entrez gene - 423102     See in Manteia.
RefSeq - XM_015286616
RefSeq - NM_001012896
RefSeq - XM_015286613
RefSeq - XM_015286614
RefSeq Peptide - NP_001012914
swissprot - E1C866
swissprot - A0A1D5NV94
Ensembl - ENSGALG00000006799
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ap2a1ENSDARG00000054320Danio rerio
 AP2A2ENSG00000183020Homo sapiens
 Ap2a2ENSMUSG00000002957Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002553  Clathrin/coatomer adaptor, adaptin-like, N-terminal
 IPR003164  Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain
 IPR008152  Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
 IPR009028  Coatomer/calthrin adaptor appendage, C-terminal subdomain
 IPR011989  Armadillo-like helical
 IPR013041  Clathrin adaptor, appendage, Ig-like subdomain superfamily
 IPR016024  Armadillo-type fold
 IPR017104  Adaptor protein complex AP-2, alpha subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0072583 clathrin-dependent endocytosis IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IEA
 cellular_componentGO:0030131 clathrin adaptor complex IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0008565 protein transporter activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0035615 clathrin adaptor activity IEA
 molecular_functionGO:0097718 disordered domain specific binding IEA


Pathways (from Reactome)
Pathway description
Retrograde neurotrophin signalling
MHC class II antigen presentation
EPH-ephrin mediated repulsion of cells
Trafficking of GluR2-containing AMPA receptors
Recycling pathway of L1
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Neutrophil degranulation
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDLR internalisation and degradation
LDL clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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