ENSGALG00000007700


Gallus gallus

Features
Gene ID: ENSGALG00000007700
  
Biological name :CTTN
  
Synonyms : CTTN / src substrate protein p85 precursor
  
Possible biological names infered from orthology : cortactin / Q14247 / Q60598
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 17890386
Gene end: 17910730
  
Corresponding Affymetrix probe sets: Gga.16258.1.S1_at (Chicken Array)   Gga.3635.1.S1_at (Chicken Array)   Gga.3635.1.S2_at (Chicken Array)   Gga.3635.2.S1_a_at (Chicken Array)   Gga.3635.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000057528
Ensembl peptide - ENSGALP00000012463
NCBI entrez gene - 396455     See in Manteia.
RefSeq - XM_015286769
RefSeq - XM_015286766
RefSeq - XM_015286767
RefSeq - XM_015286768
RefSeq - NM_205468
RefSeq - XM_015286762
RefSeq - XM_015286763
RefSeq - XM_015286764
RefSeq - XM_015286765
RefSeq Peptide - NP_990799
swissprot - F1NU55
swissprot - A0A1D5PX37
Ensembl - ENSGALG00000007700
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cttnENSDARG00000011777Danio rerio
 CTTNENSG00000085733Homo sapiens
 CttnENSMUSG00000031078Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HCLS1 / P14317* / P49710* / hematopoietic cell-specific Lyn substrate 1* / Hematopoietic lineage cell-specific protein *ENSGALG0000003968245
DBN1 / drebrin / Q16643* / Q9QXS6* / drebrin 1*ENSGALG0000003340512


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR003134  Hs1/Cortactin
 IPR015503  Cortactin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006930 substrate-dependent cell migration, cell extension IEA
 biological_processGO:0030041 actin filament polymerization IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IEA
 biological_processGO:0045987 positive regulation of smooth muscle contraction IEA
 biological_processGO:0097062 dendritic spine maintenance IEA
 biological_processGO:1903146 regulation of autophagy of mitochondrion IEA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0002102 podosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005884 actin filament IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030863 cortical cytoskeleton IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:1990023 mitotic spindle midzone IEA
 molecular_functionGO:0005522 profilin binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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