ENSGALG00000007762


Gallus gallus

Features
Gene ID: ENSGALG00000007762
  
Biological name :CREBBP
  
Synonyms : CREB binding protein / CREBBP
  
Possible biological names infered from orthology : Q92793
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 12542573
Gene end: 12622755
  
Corresponding Affymetrix probe sets: Gga.14724.1.S1_a_at (Chicken Array)   GgaAffx.4832.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049026
Ensembl peptide - ENSGALP00000054729
Ensembl peptide - ENSGALP00000038776
NCBI entrez gene - 416667     See in Manteia.
RefSeq - XM_015294628
RefSeq - XM_015294625
RefSeq - XM_015294626
RefSeq - XM_015294627
RefSeq - XM_015294622
RefSeq - XM_015294623
RefSeq - XM_015294624
swissprot - A0A1D5PPD0
swissprot - F1NGB5
swissprot - A0A1D5P8H8
Ensembl - ENSGALG00000007762
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crebbpaENSDARG00000104609Danio rerio
 crebbpbENSDARG00000112452Danio rerio
 CREBBPENSG00000005339Homo sapiens
 CrebbpENSMUSG00000022521Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EP300 / E1A binding protein p300 / B2RWS6* / Q09472* / Histone acetyltransferase p300 *ENSGALG0000001199261
BAZ2B / bromodomain adjacent to zinc finger domain protein 2B / Q9UIF8* / bromodomain adjacent to zinc finger domain 2B*ENSGALG000000125798
BRD2 / bromodomain-containing protein 2 / P25440* / Q7JJ13* / bromodomain containing 2*ENSGALG000000001567
BRD3 / bromodomain containing 3 / Q15059* / Q8K2F0* / Bromodomain-containing protein 3 *ENSGALG000000026827
BAZ2A / bromodomain adjacent to zinc finger domain 2A / Q9UIF9*ENSGALG000000295886
BRDT / bromodomain testis associated / Q58F21* / Q91Y44* / Bromodomain testis-specific protein *ENSGALG000000060316
BAZ1B / bromodomain adjacent to zinc finger domain 1B / Q9UIG0* / Q9Z277* / Tyrosine-protein kinase BAZ1B *ENSGALG000000294085
BAZ1A* / O88379* / Q9NRL2* / bromodomain adjacent to zinc finger domain 1A* / Bromodomain adjacent to zinc finger domain protein 1A *ENSGALG000000100304
BAZ1A* / O88379* / Q9NRL2* / bromodomain adjacent to zinc finger domain 1A* / Bromodomain adjacent to zinc finger domain protein 1A *ENSGALG000000315881
BAZ1A* / O88379* / Q9NRL2* / bromodomain adjacent to zinc finger domain 1A* / Bromodomain adjacent to zinc finger domain protein 1A *ENSGALG000000336471


Protein motifs (from Interpro)
Interpro ID Name
 IPR000197  Zinc finger, TAZ-type
 IPR000433  Zinc finger, ZZ-type
 IPR001487  Bromodomain
 IPR003101  Coactivator CBP, KIX domain
 IPR009110  Nuclear receptor coactivator, interlocking
 IPR010303  CREB-binding protein/p300, atypical RING domain
 IPR013178  Histone acetyltransferase Rtt109/CBP
 IPR014744  Nuclear receptor coactivator, CREB-bp-like, interlocking
 IPR018359  Bromodomain, conserved site
 IPR031162  CBP/p300-type histone acetyltransferase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006473 protein acetylation IEA
 biological_processGO:0009408 response to heat IDA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0018076 N-terminal peptidyl-lysine acetylation IEA
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0034644 cellular response to UV IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 cellular_componentGO:0000123 histone acetyltransferase complex IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016604 nuclear body IEA
 molecular_functionGO:0000987 proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0002039 p53 binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0003712 transcription coregulator activity IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016407 acetyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0043426 MRF binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of gene expression by Hypoxia-inducible Factor
Formation of the beta-catenin:TCF transactivating complex
Attenuation phase
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
CD209 (DC-SIGN) signaling
Activation of the TFAP2 (AP-2) family of transcription factors
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
RUNX3 regulates NOTCH signaling
Estrogen-dependent gene expression
TRAF6 mediated IRF7 activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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