ENSGALG00000008368


Gallus gallus

Features
Gene ID: ENSGALG00000008368
  
Biological name :RAD18
  
Synonyms : E3 ubiquitin-protein ligase RAD18 / RAD18
  
Possible biological names infered from orthology : Q9NS91 / Q9QXK2 / RAD18, E3 ubiquitin protein ligase
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 19335198
Gene end: 19369470
  
Corresponding Affymetrix probe sets: Gga.15301.1.A1_at (Chicken Array)   Gga.15301.1.S1_at (Chicken Array)   Gga.2895.1.S1_a_at (Chicken Array)   Gga.2895.3.S1_at (Chicken Array)   GgaAffx.12938.12.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013608
Ensembl peptide - ENSGALP00000060140
Ensembl peptide - ENSGALP00000054937
Ensembl peptide - ENSGALP00000051033
NCBI entrez gene - 416114     See in Manteia.
RefSeq - NM_001030603
RefSeq - XM_015293122
RefSeq Peptide - NP_001025774
swissprot - A0A1L1RMX1
swissprot - F1NVL6
swissprot - A0A1D5PPY0
swissprot - A0A1D5PE34
Ensembl - ENSGALG00000008368
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rad18ENSDARG00000027938Danio rerio
 RAD18ENSG00000070950Homo sapiens
 Rad18ENSMUSG00000030254Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR003034  SAP domain
 IPR006642  Zinc finger, Rad18-type putative
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006301 postreplication repair IBA
 biological_processGO:0006513 protein monoubiquitination IBA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0009411 response to UV IBA
 biological_processGO:0051865 protein autoubiquitination IEA
 biological_processGO:0051984 positive regulation of chromosome segregation IEA
 biological_processGO:0060548 negative regulation of cell death IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005657 replication fork IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0035861 site of double-strand break IEA
 cellular_componentGO:0042405 nuclear inclusion body IEA
 cellular_componentGO:0097505 Rad6-Rad18 complex IBA
 molecular_functionGO:0000403 Y-form DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043142 single-stranded DNA-dependent ATPase activity IBA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Recognition of DNA damage by PCNA-containing replication complex
E3 ubiquitin ligases ubiquitinate target proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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