ENSGALG00000008582


Gallus gallus

Features
Gene ID: ENSGALG00000008582
  
Biological name :ADAM23
  
Synonyms : ADAM23 / disintegrin and metalloproteinase domain-containing protein 23
  
Possible biological names infered from orthology : ADAM metallopeptidase domain 23 / O75077 / Q9R1V7
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 12503089
Gene end: 12568588
  
Corresponding Affymetrix probe sets: GgaAffx.5402.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050994
Ensembl peptide - ENSGALP00000053491
Ensembl peptide - ENSGALP00000013959
NCBI entrez gene - 424099     See in Manteia.
RefSeq - XM_015289434
RefSeq - XM_015289430
RefSeq - XM_015289431
RefSeq - XM_015289432
RefSeq - XM_015289433
RefSeq - NM_001145230
RefSeq - XM_015289427
RefSeq - XM_015289428
RefSeq - XM_015289429
RefSeq Peptide - NP_001138702
swissprot - A0A1D5PKX8
swissprot - F1NYC6
swissprot - A0A1D5PDZ6
Ensembl - ENSGALG00000008582
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adam23aENSDARG00000062323Danio rerio
 FO818722.1ENSDARG00000112453Danio rerio
 ADAM23ENSG00000114948Homo sapiens
 Adam23ENSMUSG00000025964Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADAM11 / ADAM metallopeptidase domain 11 / O75078* / Q9R1V4* / Disintegrin and metalloproteinase domain-containing protein 11 *ENSGALG0000003567345
ADAM22 / ADAM metallopeptidase domain 22 / Q9P0K1* / Q9R1V6* / Disintegrin and metalloproteinase domain-containing protein 22 *ENSGALG0000000897640
ADAM12 / disintegrin and metalloproteinase domain-containing protein 12 isoform 2 precursor / O43184* / Q61824* / ADAM metallopeptidase domain 12* / Disintegrin and metalloproteinase domai...ENSGALG0000004125529
ADAM19 / ADAM metallopeptidase domain 19 / O35674* / Q9H013* / Disintegrin and metalloproteinase domain-containing protein 19 *ENSGALG0000000374427
ADAM33 / disintegrin and metalloproteinase domain-containing protein 33 precursor / Q923W9* / Q9BZ11* / ADAM metallopeptidase domain 33* / Disintegrin and metalloproteinase domain-containi...ENSGALG0000003060227


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR013032  EGF-like, conserved site
 IPR018358  Disintegrin, conserved site
 IPR024079  Metallopeptidase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA


Pathways (from Reactome)
Pathway description
LGI-ADAM interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000043283 LGI2 / leucine-rich repeat LGI family member 2 precursor / Q8K4Z0* / Q8N0V4* / leucine rich repeat LGI family member 2*  / complex / reaction






 

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